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Gene Information

Gene symbol: ARMS2

Gene name: age-related maculopathy susceptibility 2

HGNC ID: 32685

Synonyms: LOC387715

Related Genes

# Gene Symbol Number of hits
1 AMDP1 1 hits
2 CFH 1 hits
3 HTRA1 1 hits

Related Sentences

# PMID Sentence
1 19197355 By using an additive model of the CFH, LOC387715, and C2 variants, the odds ratios are 2.9, 3.4, and 0.4, with p-values of 10(-13), 10(-13), and 10(-3), respectively.
2 22155603 After controlling for established AMD risk factors, including polymorphisms of the genes encoding complement factor H (CFH) and age-related maculopathy susceptibility 2/HtrA serine peptidase (ARMS2/HTRA1), and smoking history, we found that ultraviolet irradiance was protective for the development of neovascular AMD (p = 0.001).
3 22155603 Based on the relationship between ultraviolet irradiance and vitamin D production, we employed a candidate gene approach for evaluating common variation in key vitamin D pathway genes (the genes encoding the vitamin D receptor [VDR]; cytochrome P450, family 27, subfamily B, polypeptide 1 [CYP27B1]; cytochrome P450, family 24, subfamily A, polypeptide 1 [CYP24A1]; and CYP27A1) in this same family-based cohort.
4 23296223 [Role of CFH and ARMS2 polymorphisms in retinopathy and coronary artery disease in type 1 diabetes].