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Gene Information
Gene symbol: ARNTL2
Gene name: aryl hydrocarbon receptor nuclear translocator-like 2
HGNC ID: 18984
Synonyms: BMAL2, MOP9, CLIF, PASD9, bHLHe6
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ARNT | 1 hits |
| 2 | ARNTL | 1 hits |
| 3 | CD4 | 1 hits |
| 4 | CLOCK | 1 hits |
| 5 | MIA3 | 1 hits |
| 6 | PLA2G4A | 1 hits |
| 7 | SERPINE1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16893914 | This subinterval contains the circadian rhythm-related transcription factor Arntl2 (Bmal2), a homologue of the type 2 diabetes-associated ARNT (HIF1beta) gene. |
| 2 | 16893914 | Arntl2 upregulation was not associated with changes in the expression levels of other circadian genes in the spleen, but did correlate with the upregulation of the ARNT-binding motif containing Pla2g4a gene, which has recently been described as being protective for the progression of insulitis and autoimmune diabetes in the NOD mouse via regulation of the tumour necrosis factor-alpha pathway. |
| 3 | 16893914 | This subinterval contains the circadian rhythm-related transcription factor Arntl2 (Bmal2), a homologue of the type 2 diabetes-associated ARNT (HIF1beta) gene. |
| 4 | 16893914 | Arntl2 upregulation was not associated with changes in the expression levels of other circadian genes in the spleen, but did correlate with the upregulation of the ARNT-binding motif containing Pla2g4a gene, which has recently been described as being protective for the progression of insulitis and autoimmune diabetes in the NOD mouse via regulation of the tumour necrosis factor-alpha pathway. |
| 5 | 19387897 | The circadian expression of PAI-1 gene is thought to be directly regulated by the circadian clock proteins such as CLOCK and BMAL1/BMAL2 which drive the endogenous biological clock. |
| 6 | 20880188 | Our previous studies of the murine genetic locus Idd6 revealed the aryl hydrocarbon receptor nuclear translocator-like protein 2 (Arntl2) as a candidate gene for type 1 diabetes; and in Idd6 NOD.C3H congenic mice, Arntl2 upregulation is linked to decreased diabetes development. 2. |
| 7 | 20880188 | Diabetes incidence was increased by Arntl2 mRNA interference in the congenic strain and this was associated with an increase in CD4(+) T cells and a decrease in regulatory T cells in the peripheral immune system. 4. |
| 8 | 20880188 | Our previous studies of the murine genetic locus Idd6 revealed the aryl hydrocarbon receptor nuclear translocator-like protein 2 (Arntl2) as a candidate gene for type 1 diabetes; and in Idd6 NOD.C3H congenic mice, Arntl2 upregulation is linked to decreased diabetes development. 2. |
| 9 | 20880188 | Diabetes incidence was increased by Arntl2 mRNA interference in the congenic strain and this was associated with an increase in CD4(+) T cells and a decrease in regulatory T cells in the peripheral immune system. 4. |