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Gene Information

Gene symbol: ASAH1

Gene name: N-acylsphingosine amidohydrolase (acid ceramidase) 1

HGNC ID: 735

Synonyms: AC, PHP32, FLJ21558

Related Genes

# Gene Symbol Number of hits
1 ADCY7 1 hits
2 ASAH2 1 hits

Related Sentences

# PMID Sentence
1 15695615 Chlortetracycline analysis revealed that pertussis toxin abolished responses to AII, suggesting the involvement of an inhibitory Galpha subunit; dideoxyadenosine, a specific membrane-associated adenylyl cyclase (mAC) P-site inhibitor, also blocked responses, suggesting involvement of an mAC. cAMP determinations confirmed that both reagents also abolished AII's stimulation of cAMP.
2 17064658 Acid ceramidase (N-acylsphingosine deacylase, EC 3.5.1.23; AC) is the lipid hydrolase responsible for the degradation of ceramide into sphingosine and free fatty acids within lysosomes.