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Gene Information
Gene symbol: ASAH1
Gene name: N-acylsphingosine amidohydrolase (acid ceramidase) 1
HGNC ID: 735
Synonyms: AC, PHP32, FLJ21558
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
15695615
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Chlortetracycline analysis revealed that pertussis toxin abolished responses to AII, suggesting the involvement of an inhibitory Galpha subunit; dideoxyadenosine, a specific membrane-associated adenylyl cyclase (mAC) P-site inhibitor, also blocked responses, suggesting involvement of an mAC. cAMP determinations confirmed that both reagents also abolished AII's stimulation of cAMP.
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2 |
17064658
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Acid ceramidase (N-acylsphingosine deacylase, EC 3.5.1.23; AC) is the lipid hydrolase responsible for the degradation of ceramide into sphingosine and free fatty acids within lysosomes.
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