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Gene Information
Gene symbol: ASAH2
Gene name: N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
HGNC ID: 18860
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ASAH1 | 1 hits |
| 2 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15774472 | Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling. |
| 2 | 15774472 | Biophys. 419, 101-109), long-chain saturated FFAs inhibited insulin stimulation of Akt/protein kinase B, a central regulator of glucose uptake and anabolic metabolism. |
| 3 | 15774472 | To determine the contribution of either sphingolipid in FFA-dependent inhibition of insulin action, we generated C2C12 myotubes that constitutively overexpress acid ceramidase (AC), an enzyme that catalyzes the lysosomal conversion of ceramide to sphingosine. |
| 4 | 15774472 | Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling. |
| 5 | 15774472 | Biophys. 419, 101-109), long-chain saturated FFAs inhibited insulin stimulation of Akt/protein kinase B, a central regulator of glucose uptake and anabolic metabolism. |
| 6 | 15774472 | To determine the contribution of either sphingolipid in FFA-dependent inhibition of insulin action, we generated C2C12 myotubes that constitutively overexpress acid ceramidase (AC), an enzyme that catalyzes the lysosomal conversion of ceramide to sphingosine. |
| 7 | 17064658 | Acid ceramidase (N-acylsphingosine deacylase, EC 3.5.1.23; AC) is the lipid hydrolase responsible for the degradation of ceramide into sphingosine and free fatty acids within lysosomes. |