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Gene Information
Gene symbol: C10orf46
Gene name: chromosome 10 open reading frame 46
HGNC ID: 23727
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | COPS8 | 1 hits |
| 2 | DDIT3 | 1 hits |
| 3 | IL31RA | 1 hits |
| 4 | IRS1 | 1 hits |
| 5 | PARK2 | 1 hits |
| 6 | RNF123 | 1 hits |
| 7 | RPS27A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16871767 | Neddylation is the process that conjugates the ubiquitin-like polypeptide Nedd8 to the conserved lysines of cullins. |
| 2 | 16871767 | Cullin family proteins organize ubiquitin ligase complexes to target numerous cellular proteins for polyubiquitinylation and subsequent proteasomal degradation. |
| 3 | 23045529 | Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination. |
| 4 | 23213463 | The COP9 signalosome, cullin 3 and Keap1 supercomplex regulates CHOP stability and adipogenesis. |
| 5 | 23213463 | Here we investigate the impact of the COP9 signalosome (CSN), a regulator of cullin-RING ubiquitin ligases (CRLs), and of C/EBP homologous protein (CHOP) on the differentiation of LiSa-2 preadipocytes. |
| 6 | 23213463 | CHOP induced by piceatannol or by permanent overexpression in LiSa-2 cells blocks adipocyte differentiation as characterized by inhibited fat droplet formation and vascular endothelial growth factor (VEGF) production. |
| 7 | 23213463 | The effect of the CSN knockdown on CHOP stability can be explained by the protection of the CRL component Keap1 by the CSN associated ubiquitin-specific protease 15 (USP15). |
| 8 | 23213463 | Pulldowns and glycerol gradients reveal that CHOP interacts with a supercomplex consisting of the CSN, cullin 3 and Keap1. |