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Gene Information
Gene symbol: CACNA1I
Gene name:
HGNC ID:
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
23671274
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Trx depletion (using auranofin, 2-5 μM) reduced Cav3.2 currents and their CO sensitivity by >50% but increased sensitivity to dithiothreitol ∼3-fold.
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2 |
23671274
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By contrast, Cav3.1 and Cav3.3 channels, and their sensitivity to CO, were unaffected in identical experiments.
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3 |
23671274
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Our data propose a novel signaling pathway in which Trx acts as a tonic, endogenous regulator of Cav3.2 channels, while HO-1-derived CO disrupts this regulation, causing channel inhibition.
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