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Gene Information
Gene symbol: CALM1
Gene name: calmodulin 1 (phosphorylase kinase, delta)
HGNC ID: 1442
Synonyms: CAMI, PHKD, DD132
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACTC1 | 1 hits |
| 2 | ADCY10 | 1 hits |
| 3 | ATP2A2 | 1 hits |
| 4 | CACNA1C | 1 hits |
| 5 | CACNA1G | 1 hits |
| 6 | CACNA1H | 1 hits |
| 7 | CACNA2D1 | 1 hits |
| 8 | MYH6 | 1 hits |
| 9 | MYH7 | 1 hits |
| 10 | MYL2 | 1 hits |
| 11 | PHKA1 | 1 hits |
| 12 | PPARGC1A | 1 hits |
| 13 | PYGM | 1 hits |
| 14 | TNNI3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 6751327 | Ca2+ (10 microM)-calmodulin (1 microM) stimulated adenylate cyclase activity 53.1 +/- 5.2 (N = 6)% in the particulate fraction of rat islets. |
| 2 | 6751327 | In contrast, however, Ca2+ (1-100 microM)-calmodulin (1-10 microM) did not stimulate the adenylate cyclase activity in the EGTA-washed particulate fraction of mouse islets, and trifluoperazine (50 microM) did not inhibit the adenylate cyclase activity of this fraction of mouse islets, although some remaining calmodulin [0.18 +/- 0.05 (n = 3) microgram/mg of protein] could be demonstrated. |
| 3 | 6751327 | Ca2+ (10 microM)-calmodulin (1 microM) stimulated adenylate cyclase activity 53.1 +/- 5.2 (N = 6)% in the particulate fraction of rat islets. |
| 4 | 6751327 | In contrast, however, Ca2+ (1-100 microM)-calmodulin (1-10 microM) did not stimulate the adenylate cyclase activity in the EGTA-washed particulate fraction of mouse islets, and trifluoperazine (50 microM) did not inhibit the adenylate cyclase activity of this fraction of mouse islets, although some remaining calmodulin [0.18 +/- 0.05 (n = 3) microgram/mg of protein] could be demonstrated. |
| 5 | 21216827 | Expression of genes encoding various L-type Ca(2+) channel proteins (Cacna1c, Cacna1g, Cacna1h and Cacna2d1) and cardiac muscle proteins (Myh7) were upregulated, and genes encoding intracellular Ca(2+) transport regulatory proteins (Atp2a2 and Calm1) and some cardiac muscle proteins (Myh6, Myl2, Actc1, Tnni3, Tnn2, and Tnnc1) were downregulated in ZDF heart compared with control heart. |
| 6 | 21216827 | A change in the expression of genes encoding myosin heavy chain and L-type Ca(2+) channel proteins might partly underlie alterations in the time course of contraction and Ca(2+) transients in ventricular myocytes from ZDF rats. |
| 7 | 22272266 | The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) is a chief activator of mitochondrial and metabolic programs and protects against atrophy in skeletal muscle (skm). |
| 8 | 22272266 | The other most significantly associated GOs for the upregulated genes were chemotaxis and cytokine activity, and several cytokines, including IL-8/CXCL8, CXCL6, CCL5 and CCL8, were within the most highly induced genes. |
| 9 | 22272266 | Indeed, PGC-1α highly increased IL-8 cell protein content. |
| 10 | 22272266 | The mRNA and protein level of FITM1/FIT1, which enhances the formation of lipid droplets, was raised by PGC-1α, while in oleate-incubated cells PGC-1α increased the number of smaller lipid droplets and modestly triglyceride levels, compared to controls. |
| 11 | 22272266 | CALM1, the calcium-modulated δ subunit of phosphorylase kinase, was downregulated by PGC-1α, while glycogen phosphorylase was inactivated and glycogen storage was increased by PGC-1α. |
| 12 | 22272266 | Several myokine genes, including IL-8 and CCL5, which are known to be constitutively expressed in human skm cells, were induced by PGC-1α. |