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Gene Information
Gene symbol: CALR3
Gene name: calreticulin 3
HGNC ID: 20407
Synonyms: CRT2, FLJ25355, MGC26577, CT93
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21633399
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Our results indicate that, compared to healthy controls, individuals with metabolic syndrome have elevated mRNA levels of genes indicative of ER stress; including spliced XBP-1 (sXBP-1), Grp78, and CHOP.
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2 |
21633399
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Furthermore, in healthy individuals, a standard 75 g oral glucose challenge produced a significant elevation in spliced XBP-1 (1.3 fold), Grp78 (2.0 fold), and calreticulin (3.5 fold) mRNA 60 min post challenge and a significant increase in Grp78 (2.0 fold), calreticulin (2.7 fold) protein levels 2 h postchallenge, relative to fasting levels.
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3 |
21633399
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The oral glucose challenge was associated with a significant increase in the expression of inflammatory cytokines, including interleukin (IL)-1α/β, IL-6, and IL-8, that may result from ER stress.
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