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Gene Information
Gene symbol: CAMK2B
Gene name: calcium/calmodulin-dependent protein kinase II beta
HGNC ID: 1461
Synonyms: CAM2, CAMK2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | MAG | 1 hits |
| 2 | MAP2 | 1 hits |
| 3 | MOG | 1 hits |
| 4 | PCP4 | 1 hits |
| 5 | RAB3A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11522668 | A low-affinity Ca2+-dependent association of calmodulin with the Rab3A effector domain inversely correlates with insulin exocytosis. |
| 2 | 11522668 | As Rab3A is a model protein involved in regulated exocytosis, we have focused on its role in regulating insulin exocytosis. |
| 3 | 11522668 | Coimmunoprecipitation analysis from pancreatic islets confirmed a Rab3A-calmodulin interaction in vivo, and that it inversely correlated with insulin exocytosis. |
| 4 | 11522668 | However, Rab3A affinity for calmodulin was relatively low (Kd = 18-22 micromol/l at 10(-5) mol/l [Ca2+]) and competed by other calmodulin-binding proteins that had higher affinity (e.g., Ca2+/calmodulin-dependent protein kinase-2 [CaMK-2] [Kd = 300-400 nmol/l at 10(-5) mol/l [Ca2+]]). |
| 5 | 11522668 | The data suggested that a transient Rab3A-calmodulin interaction might represent a means of directing calmodulin to the cytoplasmic face of a beta-granule, where it can be subsequently transferred for activation of other beta-granule-associated calmodulin-binding proteins as local [Ca2+]i rises to promote insulin exocytosis. |
| 6 | 15234464 | The expression of the phosphodiesterase Enpp2, myelin oligodendrocyte glycoprotein (Mog), microtubule-associated protein 2 (MAP2), growth hormone (GH), Ca(2+)/calmodulin-dependent protein kinase beta-subunit (Camk2b), neuron-specific protein PEP-19 (Pcp4), a sodium-dependent neurotransmitter, and the myelin-associated glycoprotein (S-MAG) was significantly increased. |
| 7 | 15234464 | Three genes were suppressed by hyperthyroidism, including the activity and neurotransmitter-induced early genes-1 and -7 (ANIA-1 and ANIA-7) and the guanine nucleotide-binding protein one (Gnb1). |