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Gene Information
Gene symbol: CASP14
Gene name: caspase 14, apoptosis-related cysteine peptidase
HGNC ID: 1502
Synonyms: MICE, MGC119078, MGC119079
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CASP7 | 1 hits |
| 2 | CASP8 | 1 hits |
| 3 | S100A8 | 1 hits |
| 4 | SOSTDC1 | 1 hits |
| 5 | VDR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 14679087 | Caspase 7 is a positional candidate gene for IDDM 17 in a Bedouin Arab family. |
| 2 | 14679087 | Caspase 7 (CASP7), an apoptosis-related cysteine protease, is one of the few known genes in this region. |
| 3 | 22782502 | When occupied by 1,25D, VDR interacts with the retinoid X receptor (RXR) to form a heterodimer that binds to vitamin D responsive elements in the region of genes directly controlled by 1,25D. |
| 4 | 22782502 | For example, 1,25D induces RANKL, SPP1 (osteopontin), and BGP (osteocalcin) to govern bone mineral remodeling; TRPV6, CaBP(9k), and claudin 2 to promote intestinal calcium absorption; and TRPV5, klotho, and Npt2c to regulate renal calcium and phosphate reabsorption. |
| 5 | 22782502 | VDR appears to function unliganded by 1,25D in keratinocytes to drive mammalian hair cycling via regulation of genes such as CASP14, S100A8, SOSTDC1, and others affecting Wnt signaling. |