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Gene Information
Gene symbol: CDC16
Gene name: cell division cycle 16 homolog (S. cerevisiae)
HGNC ID: 1720
Synonyms: APC6, ANAPC6, CUT9
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDC27 | 1 hits |
| 2 | PAK1IP1 | 1 hits |
| 3 | TBC1D1 | 1 hits |
| 4 | TBC1D4 | 1 hits |
| 5 | USP6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2823230 | The start of the CDC16 ORF is only 95 bp downstream from the end of the MAK11 ORF. |
| 2 | 11134076 | These mutants, representing six different complementation groups, all map near genes that encode subunits of the anaphase promoting complex or cyclosome, and, here, we show that one of the genes, emb-27, encodes the C. elegans CDC16 ortholog. |
| 3 | 23045393 | The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes. |
| 4 | 23045393 | The Rab GTPase-activating protein TBC1D4/AS160 regulates GLUT4 trafficking in adipocytes. |
| 5 | 23045393 | Nonphosphorylated AS160 binds to GLUT4 vesicles and inhibits GLUT4 translocation, and AS160 phosphorylation overcomes this inhibitory effect. |
| 6 | 23045393 | The second phosphotyrosine-binding domain in AS160 encodes a phospholipid-binding domain that facilitates plasma membrane (PM) targeting of AS160, and this function is conserved in other related RabGAP/Tre-2/Bub2/Cdc16 (TBC) proteins and an AS160 ortholog in Drosophila. |
| 7 | 23045393 | The interaction of AS160 with GSVs and not with the PM confers the inhibitory effect of AS160 on insulin-dependent GLUT4 translocation. |
| 8 | 23045393 | Constitutive targeting of AS160 to the PM increased the surface GLUT4 levels, and this was attributed to both enhanced AS160 phosphorylation and 14-3-3 binding and inhibition of AS160 GAP activity. |