Ignet

Gene Information

Gene symbol: CDK2AP2

Gene name: cyclin-dependent kinase 2 associated protein 2

HGNC ID: 30833

Synonyms: DOC-1R, p14

Related Genes

#	Gene Symbol	Number of hits
1	C2orf28	1 hits
2	CASP3	1 hits
3	CDKN2A	1 hits
4	COL1A1	1 hits
5	EXOSC1	1 hits
6	GAD1	1 hits
7	INS	1 hits
8	POLE3	1 hits
9	PRL	1 hits
10	RIPK1	1 hits
11	TP53	1 hits

Related Sentences

#	PMID	Sentence
1	2775272	Recently we identified five novel peptides of Mr 13,000 to 18,000 (designated P13, P14, P16, P17, and P18 according to approximate Mr) in the anterior pituitary gland of rat and man that appeared related to GH and PRL in regulation and structure.
2	2775272	We have now raised polyclonal antibodies in the rabbit to four of these peptides--P13, P14, P17 and P18--isolated from rat anterior pituitary; the rabbit injected with P16 did not produce antibodies.
3	2775272	Antiserum to P17, in addition, crossreacted very strongly with rat PRL, while P18 antiserum crossreacted not only with human GH but also with its 20K and cleaved variants.
4	2775272	Recently we identified five novel peptides of Mr 13,000 to 18,000 (designated P13, P14, P16, P17, and P18 according to approximate Mr) in the anterior pituitary gland of rat and man that appeared related to GH and PRL in regulation and structure.
5	2775272	We have now raised polyclonal antibodies in the rabbit to four of these peptides--P13, P14, P17 and P18--isolated from rat anterior pituitary; the rabbit injected with P16 did not produce antibodies.
6	2775272	Antiserum to P17, in addition, crossreacted very strongly with rat PRL, while P18 antiserum crossreacted not only with human GH but also with its 20K and cleaved variants.
7	3178830	Electrophoretic analysis of murine anterior pituitary extract revealed five major proteins of Mr 13,000-18,000 (designated P13, P14, P16, P17, and P18 according to Mr), three of which, P16, P17, and P18, were markedly influenced by estradiol benzoate and perphenazine in a manner similar to that of growth hormone, and two, P13 and P14, to that of prolactin.
8	3178830	Tyrosine peptide mapping showed partial resemblance of fingerprints for P16 and P17 (and possibly P18) to those for growth hormone, and of P13 and P14 to those for prolactin.
9	3178830	Both P14 and P18 bound to Concanavalin A.
10	3178830	The concentrations of P13 and P14 in pituitaries from lactating rats and in a prolactinoma were distinctly higher than normal.
11	3178830	These results suggest that P16, P17 and P18 are growth hormone- and P13 and P14 prolactin-related secretory proteins of the pituitary.
12	3178830	Electrophoretic analysis of murine anterior pituitary extract revealed five major proteins of Mr 13,000-18,000 (designated P13, P14, P16, P17, and P18 according to Mr), three of which, P16, P17, and P18, were markedly influenced by estradiol benzoate and perphenazine in a manner similar to that of growth hormone, and two, P13 and P14, to that of prolactin.
13	3178830	Tyrosine peptide mapping showed partial resemblance of fingerprints for P16 and P17 (and possibly P18) to those for growth hormone, and of P13 and P14 to those for prolactin.
14	3178830	Both P14 and P18 bound to Concanavalin A.
15	3178830	The concentrations of P13 and P14 in pituitaries from lactating rats and in a prolactinoma were distinctly higher than normal.
16	3178830	These results suggest that P16, P17 and P18 are growth hormone- and P13 and P14 prolactin-related secretory proteins of the pituitary.
17	3178830	Electrophoretic analysis of murine anterior pituitary extract revealed five major proteins of Mr 13,000-18,000 (designated P13, P14, P16, P17, and P18 according to Mr), three of which, P16, P17, and P18, were markedly influenced by estradiol benzoate and perphenazine in a manner similar to that of growth hormone, and two, P13 and P14, to that of prolactin.
18	3178830	Tyrosine peptide mapping showed partial resemblance of fingerprints for P16 and P17 (and possibly P18) to those for growth hormone, and of P13 and P14 to those for prolactin.
19	3178830	Both P14 and P18 bound to Concanavalin A.
20	3178830	The concentrations of P13 and P14 in pituitaries from lactating rats and in a prolactinoma were distinctly higher than normal.
21	3178830	These results suggest that P16, P17 and P18 are growth hormone- and P13 and P14 prolactin-related secretory proteins of the pituitary.
22	3178830	Electrophoretic analysis of murine anterior pituitary extract revealed five major proteins of Mr 13,000-18,000 (designated P13, P14, P16, P17, and P18 according to Mr), three of which, P16, P17, and P18, were markedly influenced by estradiol benzoate and perphenazine in a manner similar to that of growth hormone, and two, P13 and P14, to that of prolactin.
23	3178830	Tyrosine peptide mapping showed partial resemblance of fingerprints for P16 and P17 (and possibly P18) to those for growth hormone, and of P13 and P14 to those for prolactin.
24	3178830	Both P14 and P18 bound to Concanavalin A.
25	3178830	The concentrations of P13 and P14 in pituitaries from lactating rats and in a prolactinoma were distinctly higher than normal.
26	3178830	These results suggest that P16, P17 and P18 are growth hormone- and P13 and P14 prolactin-related secretory proteins of the pituitary.
27	3178830	Electrophoretic analysis of murine anterior pituitary extract revealed five major proteins of Mr 13,000-18,000 (designated P13, P14, P16, P17, and P18 according to Mr), three of which, P16, P17, and P18, were markedly influenced by estradiol benzoate and perphenazine in a manner similar to that of growth hormone, and two, P13 and P14, to that of prolactin.
28	3178830	Tyrosine peptide mapping showed partial resemblance of fingerprints for P16 and P17 (and possibly P18) to those for growth hormone, and of P13 and P14 to those for prolactin.
29	3178830	Both P14 and P18 bound to Concanavalin A.
30	3178830	The concentrations of P13 and P14 in pituitaries from lactating rats and in a prolactinoma were distinctly higher than normal.
31	3178830	These results suggest that P16, P17 and P18 are growth hormone- and P13 and P14 prolactin-related secretory proteins of the pituitary.
32	10839816	We have used rat insulin promoter (RIP)-gp/P14 double-transgenic mice expressing the lymphocytic choriomeningitis virus (LCMV) glycoprotein (gp) on pancreatic beta-islet cells together with T cells expressing an LCMV-gp-specific T cell receptor to assess the requirements for the induction of autoimmunity.
33	12089067	Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells.
34	12089067	In the present study, we show that early-passage human umbilical vein endothelial cells (HUVECs) grown on glycated collagen (GC) express hallmarks of premature cell senescence, ie, increase in the proportion of cells expressing senescence-associated beta-galactosidase activity, apoptotic rate, and p53 and p14(AFR) expression, but in contrast to replicative senescence, display neither attrition of telomeres nor decrease in telomerase activity.
35	15571925	We used cDNA microarray technology to identify genes differentially regulated in splenocytes of T1D prone NOD mice after immunization with a disease protective glutamic acid decarboxylase 65 (GAD(65) P14) peptide.
36	15831467	To determine the role of caspase-3-dependent apoptosis in disease initiation, a defined antigen-T-cell receptor transgenic system, RIP-GP/P14 double-transgenic mice with Casp3 null mutation, was examined. beta-cell antigen-specific T-cell activation and proliferation were observed only in the pancreatic draining lymph node of RIP-GP/P14/Casp3(+/-) mice, but not in mice lacking caspase-3.