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Gene Information
Gene symbol: CLDN2
Gene name: claudin 2
HGNC ID: 2041
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BGLAP | 1 hits |
| 2 | CLDN1 | 1 hits |
| 3 | CLDN7 | 1 hits |
| 4 | KL | 1 hits |
| 5 | MYO9B | 1 hits |
| 6 | OCLN | 1 hits |
| 7 | S100A6 | 1 hits |
| 8 | SPP1 | 1 hits |
| 9 | TNFSF11 | 1 hits |
| 10 | TRPV6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16644703 | The increased zonulin levels correlated with increased intestinal permeability in vivo and changes in claudin-1, claudin-2, and myosin IXB genes expression, while no changes were detected in ZO1 and occludin genes expression. |
| 2 | 22782502 | When occupied by 1,25D, VDR interacts with the retinoid X receptor (RXR) to form a heterodimer that binds to vitamin D responsive elements in the region of genes directly controlled by 1,25D. |
| 3 | 22782502 | For example, 1,25D induces RANKL, SPP1 (osteopontin), and BGP (osteocalcin) to govern bone mineral remodeling; TRPV6, CaBP(9k), and claudin 2 to promote intestinal calcium absorption; and TRPV5, klotho, and Npt2c to regulate renal calcium and phosphate reabsorption. |
| 4 | 22782502 | VDR appears to function unliganded by 1,25D in keratinocytes to drive mammalian hair cycling via regulation of genes such as CASP14, S100A8, SOSTDC1, and others affecting Wnt signaling. |