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Gene Information
Gene symbol: CLEC4D
Gene name: C-type lectin domain family 4, member D
HGNC ID: 14554
Synonyms: Mpcl
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CLEC7A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20361523 | Toll-like receptors and C-type lectin receptor class V--Dectin-1, as members of Pattern Recognition Receptors play an essential role in innate immune response against bacteria and fungi respectively, contributing to pathogens recognition, phagocytosis, ROS production and induction of pro-inflammatory cytokines secretion. |
| 2 | 20361523 | These compounds blocked Dectin-1 and were able to inhibit co-operation between Dectin-1 and TLR-2. |
| 3 | 20361523 | Taking into account the fact that Dectin-1 can actively collaborate with TLR-2 to modulate the subsequent adaptive immune response, we can presume that Curdlan derivatives containing sulfopropyl group or palmithoyl/carboxi-methyl/sulfopropyl groups, as possible Dectin-1 antagonists/agonists, could influence TLR-2 signaling. |