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Gene Information
Gene symbol: CNP
Gene name: 2',3'-cyclic nucleotide 3' phosphodiesterase
HGNC ID: 2158
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
11161808
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Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse.
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2 |
11161808
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While Drosophila contains only one Stat (d-Stat), mammals contain seven, with STATs 3, 5a, and 5b being the closest functional relatives.
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3 |
11161808
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To understand the evolutionary relationship between d-Stat and vertebrate STATs 3 and 5, we isolated, sequenced, and analyzed the zebrafish Stat3 (z-Stat3) gene and a 500-kb region spanning mouse chromosome 11, 60.5 cM containing three Stat genes (m-Stats).
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4 |
11161808
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Within this region we identified the genes encoding m-Stats 3, 5a, and 5b, Cnp1, Hcrt/Orexin, Ptrf, GCN5, mDj11, and four new genes.
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5 |
11161808
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The 5' ends of the m-Stat5a and m-Stat5b genes are juxtaposed to each other, and the 3' ends of the m-Stat3 and Stat5a genes face each other.
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6 |
11161808
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We propose that the Stat3 and Stat5 lineages are derived from the duplication of a common primordial gene and that d-Stat is a part of the Stat5 lineage.
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