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Gene Information

Gene symbol: COMT

Gene name: catechol-O-methyltransferase

HGNC ID: 2228

Related Genes

# Gene Symbol Number of hits
1 ACADSB 1 hits
2 HTR3A 1 hits
3 INS 1 hits
4 SLC45A2 1 hits
5 SUCLG2 1 hits
6 SULT1C2 1 hits
7 TBXAS1 1 hits
8 UGT1A 1 hits
9 UGT1A3 1 hits
10 UGT1A8 1 hits
11 UGT2B15 1 hits

Related Sentences

# PMID Sentence
1 12010186 The role of hyperglycaemia in the lowering of COMT activity was then investigated using phlorizin or insulin at doses sufficient to normalize plasma glucose from STZ-diabetic rats.
2 12010186 Both insulin and phlorizin treatment of STZ-diabetic rats for 4 days restored the activity of COMT to that seen in normal rats.
3 12010186 The role of hyperglycaemia in the lowering of COMT activity was then investigated using phlorizin or insulin at doses sufficient to normalize plasma glucose from STZ-diabetic rats.
4 12010186 Both insulin and phlorizin treatment of STZ-diabetic rats for 4 days restored the activity of COMT to that seen in normal rats.
5 17143180 Association of genetic polymorphisms of ACADSB and COMT with human hypertension.
6 19060410 However some genes such as catechol-o-methyltransferase and succinyl-CoA synthetase were regulated by KTE, indicating that KTE is not toxic to normal mice and might be effective as a functional food.
7 19690620 Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes.
8 19999796 The final manifestation of side reactions is dependent on the genotype, especially polymorphisms of genes associated with caffeine metabolism, i.e., cytochrome P450-CYP1A2 and catechol-O-methyltransferase (COMT).
9 22859782 The diabetic status induced increased UDP-glucuronosyltransferase (UGT) 1A3, UGT1A8, UGT2B8, and sulfotransferase (SULT) 1A1 mRNA levels and decreased catechol-O-methyltransferase (COMT), UGT2B6, UGT2B12, and SULT1C1 mRNA levels.