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Gene Information

Gene symbol: CROT

Gene name: carnitine O-octanoyltransferase

HGNC ID: 2366

Synonyms: COT

Related Genes

# Gene Symbol Number of hits
1 CPT1A 1 hits
2 CRAT 1 hits
3 CS 1 hits
4 HADH 1 hits
5 HADHB 1 hits
6 INS 1 hits
7 IRS2 1 hits
8 PRKAA1 1 hits
9 SIRT6 1 hits

Related Sentences

# PMID Sentence
1 11912554 To examine the roles of carnitine-mediated transport and mitochondrial content, we also measured carnitine palmitoyltransferase I (CPT1), carnitine octanoyl transferase (COT), and citrate synthase (CS) activities.
2 11912554 CPT1 and CS activity were significantly (P <.05) higher (approximately 25%) in the endurance-trained subjects; there was no difference in COT activity.
3 11912554 To examine the roles of carnitine-mediated transport and mitochondrial content, we also measured carnitine palmitoyltransferase I (CPT1), carnitine octanoyl transferase (COT), and citrate synthase (CS) activities.
4 11912554 CPT1 and CS activity were significantly (P <.05) higher (approximately 25%) in the endurance-trained subjects; there was no difference in COT activity.
5 15591000 These enzymes include carnitine acetyltransferase (CrAT), carnitine octanoyltransferase (CrOT), and carnitine palmitoyltransferases (CPTs).
6 22156303 Interestingly, miR-33a/b also act in the fatty acid/lipid homeostasis pathway by controlling the fatty acid β-oxidation genes carnitine O-octanoyltransferase (CROT), hydroxyacyl-coenzyme A-dehydrogenase (HADHB), and carnitine palmitoyltransferase 1A (CPT1A), as well as the energy sensor AMP-activated protein kinase (AMPKα1), the NAD(+)-dependent sirtuin SIRT6, and the insulin signaling intermediate IRS2, key regulators of glucose and lipid metabolism.