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Gene Information

Gene symbol: CTNND1

Gene name: catenin (cadherin-associated protein), delta 1

HGNC ID: 2515

Synonyms: KIAA0384, p120, p120cas, p120ctn

Related Genes

# Gene Symbol Number of hits
1 JUP 1 hits
2 RHOD 1 hits

Related Sentences

# PMID Sentence
1 12438247 Reduced expression of insulin-like growth factor I receptors in MCF-7 breast cancer cells leads to a more metastatic phenotype.
2 12438247 Several lines of evidence support an important role for the insulin-like growth factor system in breast cancer.
3 12438247 Alterations in insulin-like growth factor I receptor (IGF-IR) have been associated with breast cancer metastasis; however, the specific role played by the IGF-IR in this process remains unclear.
4 12438247 Moreover, there was a significant reduction in p120 present in the E-cadherin-catenin-p120 complex.
5 12438247 There was a 2-fold increase in active Rac1 and Cdc42 and a 35% decrease in active Rho in the SX13 cells.
6 12438247 Our findings strongly suggest that the IGF-IR plays a role in the stabilization of the E-cadherin-catenin complex, thereby providing one possible explanation for the association between low levels of IGF-IR and a higher risk of mammary tumor metastasis.
7 23337773 These AJ structures are maintained by E-cadherin and catenin complexes such as β-catenin and p120 catenin.
8 23337773 In the diabetic state, enhanced Rho and Rho-kinase activity reduced p120 catenin expression and altered the distribution of p120 catenin and E-cadherin, which are normally localized in the paranodal compartment of the nodes of Ranvier and Schmidt-Lanterman incisures where autotypic AJs stabilize myelin structure.
9 23337773 Fasudil restored normal p120 catenin expression and the distribution of p120 catenin and E-cadherin in the myelin sheath.
10 23337773 These AJ structures are maintained by E-cadherin and catenin complexes such as β-catenin and p120 catenin.
11 23337773 In the diabetic state, enhanced Rho and Rho-kinase activity reduced p120 catenin expression and altered the distribution of p120 catenin and E-cadherin, which are normally localized in the paranodal compartment of the nodes of Ranvier and Schmidt-Lanterman incisures where autotypic AJs stabilize myelin structure.
12 23337773 Fasudil restored normal p120 catenin expression and the distribution of p120 catenin and E-cadherin in the myelin sheath.
13 23337773 These AJ structures are maintained by E-cadherin and catenin complexes such as β-catenin and p120 catenin.
14 23337773 In the diabetic state, enhanced Rho and Rho-kinase activity reduced p120 catenin expression and altered the distribution of p120 catenin and E-cadherin, which are normally localized in the paranodal compartment of the nodes of Ranvier and Schmidt-Lanterman incisures where autotypic AJs stabilize myelin structure.
15 23337773 Fasudil restored normal p120 catenin expression and the distribution of p120 catenin and E-cadherin in the myelin sheath.