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Gene Information
Gene symbol: CXCL6
Gene name: chemokine (C-X-C motif) ligand 6
HGNC ID: 10643
Synonyms: GCP-2, CKA-3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL5 | 1 hits |
| 2 | CCL8 | 1 hits |
| 3 | IL8 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22272266 | The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) is a chief activator of mitochondrial and metabolic programs and protects against atrophy in skeletal muscle (skm). |
| 2 | 22272266 | The other most significantly associated GOs for the upregulated genes were chemotaxis and cytokine activity, and several cytokines, including IL-8/CXCL8, CXCL6, CCL5 and CCL8, were within the most highly induced genes. |
| 3 | 22272266 | Indeed, PGC-1α highly increased IL-8 cell protein content. |
| 4 | 22272266 | The mRNA and protein level of FITM1/FIT1, which enhances the formation of lipid droplets, was raised by PGC-1α, while in oleate-incubated cells PGC-1α increased the number of smaller lipid droplets and modestly triglyceride levels, compared to controls. |
| 5 | 22272266 | CALM1, the calcium-modulated δ subunit of phosphorylase kinase, was downregulated by PGC-1α, while glycogen phosphorylase was inactivated and glycogen storage was increased by PGC-1α. |
| 6 | 22272266 | Several myokine genes, including IL-8 and CCL5, which are known to be constitutively expressed in human skm cells, were induced by PGC-1α. |