- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: CYP7B1
Gene name: cytochrome P450, family 7, subfamily B, polypeptide 1
HGNC ID: 2652
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ABCA1 | 1 hits |
| 2 | CCL2 | 1 hits |
| 3 | CNBP | 1 hits |
| 4 | CYP1A1 | 1 hits |
| 5 | CYP1A2 | 1 hits |
| 6 | CYP27A1 | 1 hits |
| 7 | CYP39A1 | 1 hits |
| 8 | CYP7A1 | 1 hits |
| 9 | CYP8B1 | 1 hits |
| 10 | GSTM3 | 1 hits |
| 11 | IL1B | 1 hits |
| 12 | IL2 | 1 hits |
| 13 | INS | 1 hits |
| 14 | LPL | 1 hits |
| 15 | NR1H3 | 1 hits |
| 16 | NR1H4 | 1 hits |
| 17 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12130701 | Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome p450 and glutathione s-transferase isoforms in a New Zealand obese-derived mouse backcross population. |
| 2 | 12130701 | In subgroups of a New Zealand obese mouse-derived backcross population with defined aberrations of glucose homeostasis, a comprehensive study of the hepatic expression of cytochrome P450 and glutathione S-transferase was performed. |
| 3 | 12130701 | Three patterns of alterations in response to insulin resistance (normoglycemia/hyperinsulinemia) or diabetes (hyperglycemia/hypoinsulinemia) were observed: mRNA levels of Cyp2b9, Cyp3a16, Cyp4a14, and Gstt2 as assessed by Northern- and dot-blot analysis were increased markedly in liver from diabetic mice with no or only a slight increase in insulin resistant mice. |
| 4 | 12130701 | Furthermore, expression of Cyp1a2, Cyp7b1, Gstm3, and Gstm6 was reduced in both diabetic and insulin resistant mice. |
| 5 | 14599559 | Hepatocyte nuclear factor 1 alpha (HNF1alpha) is a liver enriched homeodomain-containing transcription factor that has been shown to transactivate the promoters of several cytochrome P450 (CYP) genes, including CYP2E1, CYP1A2, CYP7A1, and CYP27, in vitro. |
| 6 | 14599559 | Analysis of CYP gene expression revealed marked reductions in expression of Cyp1a2, Cyp2c29 and Cyp2e1, and a moderate reduction of Cyp3a11. |
| 7 | 14599559 | There are also significant changes in the expression of genes encoding CYPs involved in fatty acid and bile acid metabolism characterized by a reduction in the expression of Cyp7b1, and Cyp27 as well as elevations in Cyp4a1/3, Cyp7a1, Cyp8b1, and Cyp39a1 expression. |
| 8 | 18587407 | Disinhibition of the forkhead transcription factor FoxO1, increases expression of the biliary cholesterol transporters Abcg5 and Abcg8, resulting in an increase in biliary cholesterol secretion. |
| 9 | 18587407 | Hepatic insulin resistance also decreases expression of the bile acid synthetic enzymes, particularly Cyp7b1, and produces partial resistance to the farnesoid X receptor, leading to a lithogenic bile salt profile. |
| 10 | 21606463 | Microarray and quantitative PCR analyses of livers from Ins2(Akita)Ldlr⁻/⁻ mice revealed altered expression of lipid homeostatic genes, including sterol-regulatory element binding protein (Srebp)1, liver X receptor (Lxr)α, Abca1, Cyp7b1, Cyp27a1, and Lpl, along with increased expression of pro-inflammatory cytokine genes, including interleukin (Il)1α, Il1β, Il2, tumor necrosis factor (Tnf)α, and Mcp1. |