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Gene Information
Gene symbol: CYTL1
Gene name: cytokine-like 1
HGNC ID: 24435
Synonyms: C17, C4orf4
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CRH | 1 hits |
| 2 | CYP11A1 | 1 hits |
| 3 | CYP17A1 | 1 hits |
| 4 | CYP2B6 | 1 hits |
| 5 | MC2R | 1 hits |
| 6 | POMC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8817242 | Whereas mitochondrial CYP11A (cytochrome P450cscc: cholesterol monooxygenase) was absolutely temperature-insensitive in all systems tested, CYP17 (cytochrome P450c17: steroid-17 alpha-monooxygenase/C17, 20-aldolase) in the smooth endoplasmic reticulum responded with a 57% loss in whole testes and 39% loss in purified Leydig cells upon a 3-hour temperature elevation from 31 degrees C to 38 degrees C. |
| 2 | 8817242 | It is concluded that CYP17, but not CYP11A, is very sensitive towards even moderate elevation of environmental temperature, and that this apparent lability is not an intrinsic property of the enzyme protein but rather mediated by heat-activated intracellular factors. |
| 3 | 11196419 | There is a progressive and concurrent increase of ACTH1-39 and cortisol (F) in the circulation of fetal sheep during the last 15-20 days of pregnancy (term, day 145-150) associated with increased expression of hypothalamic CRH pituitary POMC and adrenal ACTH receptor and steroidogenic enzymes, particularly P450 C17. |