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Gene Information
Gene symbol: DCTN5
Gene name: dynactin 5 (p25)
HGNC ID: 24594
Synonyms: MGC3248, p25
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | DNALI1 | 1 hits |
| 2 | MADCAM1 | 1 hits |
| 3 | VCAM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11472212 | Interactions of the integrins alpha(4)beta(7) with its cognate ligand mucosal addressin cell adhesion molecule-1 (MAdCAM-1) play a crucial role in the development of mucosa-associated lymphoid organs, in the generation of mucosal immune responses, and in diverse pathological processes such as chronic inflammatory bowel disease and type I diabetes. |
| 2 | 11472212 | The cyclic hexapeptide P10 cyclo(Leu-Asp-Thr-Ala-D-Pro-Ala) inhibits alpha(4)beta(7) integrin mediated cell adhesion to MAdCAM-1 effectively. |
| 3 | 11472212 | The compounds P25 cyclo(Leu-Asp-Thr-Ala-D-Pro-Phe), P28 cyclo(Leu-Asp-Thr-Asp-D-Pro-Phe), P29 cyclo(Leu-Asp-Thr-Asp-D-Pro-His), and P30 cyclo(Leu-Asp-Thr-Asp-D-Pro-Tyr) strongly inhibited alpha(4)beta(7) integrin mediated cell adhesion to MAdCAM-1, but they did not affect binding of the closely related alpha(4)beta(1) integrin to VCAM-1. |