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Gene Information
Gene symbol: DIDO1
Gene name: death inducer-obliterator 1
HGNC ID: 2680
Synonyms: DIO1, dJ885L7.8, FLJ11265, KIAA0333, DIO-1, BYE1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | SMARCA5 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16917504 | The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor. |
| 2 | 16917504 | Unliganded thyroid hormone receptor (TR) actively represses transcription via the nuclear receptor corepressor (N-CoR)/histone deacetylase 3 (HDAC3) complex. |
| 3 | 16917504 | N-CoR and HDAC3 are both required for recruitment of SNF2H to the repressed gene. |
| 4 | 16917504 | SNF2H does not interact directly with the N-CoR/HDAC3 complex, but binds to unacetylated histone H4 tails, suggesting that deacetylase activity of the corepressor complex is critical to SNF2H function. |
| 5 | 16917504 | Indeed, HDAC3 as well as SNF2H are required for nucleosomal organization on the TR target gene. |
| 6 | 16917504 | Consistent with these findings, reduction of SNF2H induces expression of an endogenous TR-regulated gene, dio1, in liver cells. |