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Gene Information

Gene symbol: DNAJA1

Gene name: DnaJ (Hsp40) homolog, subfamily A, member 1

HGNC ID: 5229

Synonyms: HSPF4, hdj-2, dj-2, NEDD7

Related Genes

#	Gene Symbol	Number of hits
1	DNAJA2	1 hits
2	DNAJC1	1 hits
3	HSPA5	1 hits
4	PARK7	1 hits
5	SERPINA12	1 hits

Related Sentences

#	PMID	Sentence
1	11754100	Two novel types of contiguous gene deletion of the AVPR2 and ARHGAP4 genes in unrelated Japanese kindreds with nephrogenic diabetes insipidus.
2	11754100	Study of two families containing individuals with nephrogenic diabetes insipidus (NDI) indicated different types of 21.3 kb and 26.3 kb deletions involving the AVPR2 and ARHGAP4 (RhoGAP C1) genes.
3	11754100	We defined three deletion junctions in this rearrangement (DJ1, DJ2, and DJ3) from the 5'-side.
4	22837305	Vaspin is an adipokine ameliorating ER stress in obesity as a ligand for cell-surface GRP78/MTJ-1 complex.
5	22837305	Here, we show that visceral adipose tissue-derived serine protease inhibitor (vaspin) binds to cell-surface 78-kDa glucose-regulated protein (GRP78), which is recruited from ER to plasma membrane under ER stress.
6	22837305	The complex formation of vaspin, GRP78, and murine tumor cell DnaJ-like protein 1 (MTJ-1) (DnaJ homolog, subfamily C, member 1) on plasma membrane was confirmed by cell-surface labeling with biotin and immunoprecipitation in liver tissues and H-4-II-E-C3 cells.
7	22837305	The addition of recombinant human vaspin in the cultured H-4-II-E-C3 cells also increased the phosphorylation of Akt and AMP-activated protein kinase (AMPK) in a dose-dependent manner, and anti-GRP78 antibodies completely abrogated the vaspin-induced upregulation of pAkt and pAMPK.
8	22837305	Vaspin is a novel ligand for cell-surface GRP78/MTJ-1 complex, and its subsequent signals exert beneficial effects on ER stress-induced metabolic dysfunctions.