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Gene Information
Gene symbol: DNAJC3
Gene name: DnaJ (Hsp40) homolog, subfamily C, member 3
HGNC ID: 9439
Synonyms: P58, P58IPK, HP58
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EIF2A | 1 hits |
| 2 | EIF2S1 | 1 hits |
| 3 | HSPA1A | 1 hits |
| 4 | INS | 1 hits |
| 5 | SEC61A1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15793246 | P58(IPK) (DNAJC3) is induced during ER stress and functions as a negative feedback component to inhibit eIF-2alpha signaling and attenuate the later phases of the ER stress response. |
| 2 | 15793246 | Insulin deficiency associated with the absence of P58(IPK) mimics beta-cell failure associated with type 1 and late-stage type 2 diabetes. |
| 3 | 15793246 | P58(IPK) (DNAJC3) is induced during ER stress and functions as a negative feedback component to inhibit eIF-2alpha signaling and attenuate the later phases of the ER stress response. |
| 4 | 15793246 | Insulin deficiency associated with the absence of P58(IPK) mimics beta-cell failure associated with type 1 and late-stage type 2 diabetes. |
| 5 | 16923392 | Here, we report that P58(IPK)/DNAJC3, a UPR-responsive gene previously implicated in translational control, encodes a cytosolic cochaperone that associates with the ER protein translocation channel Sec61. |
| 6 | 16923392 | P58(IPK) recruits HSP70 chaperones to the cytosolic face of Sec61 and can be crosslinked to proteins entering the ER that are delayed at the translocon. |
| 7 | 16923392 | Here, we report that P58(IPK)/DNAJC3, a UPR-responsive gene previously implicated in translational control, encodes a cytosolic cochaperone that associates with the ER protein translocation channel Sec61. |
| 8 | 16923392 | P58(IPK) recruits HSP70 chaperones to the cytosolic face of Sec61 and can be crosslinked to proteins entering the ER that are delayed at the translocon. |