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Gene Information
Gene symbol: EIF5A2
Gene name: eukaryotic translation initiation factor 5A2
HGNC ID: 3301
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EIF5A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22888148 | Hypusine modification of eukaryotic initiation factor 5A (eIF-5A) represents a unique and highly specific post-translational modification with regulatory functions in cancer, diabetes, and infectious diseases. |
| 2 | 22888148 | To globally characterize eIF-5A and hypusine-dependent pathways, we used an approach that combines large-scale bioreactor cell culture with tandem affinity purification and mass spectrometry: "bioreactor-TAP-MS/MS." |
| 3 | 22888148 | By applying this approach systematically to all four components of the hypusine modification system (eIF-5A1, eIF-5A2, DHS, and DOHH), we identified 248 interacting proteins as components of the cellular hypusine network, with diverse functions including regulation of translation, mRNA processing, DNA replication, and cell cycle regulation. |
| 4 | 22888148 | In addition, we validated the interaction of eIF-5A with some of the newly identified associated proteins in more detail. |