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Gene Information

Gene symbol: ERVWE1

Gene name: endogenous retroviral family W, env(C7), member 1 (syncytin)

HGNC ID: 13525

Related Genes

# Gene Symbol Number of hits
1 CD34 1 hits
2 CD38 1 hits
3 CD4 1 hits
4 GPI 1 hits
5 GTPBP1 1 hits
6 IDDM2 1 hits
7 IFNG 1 hits
8 IL10 1 hits
9 INS 1 hits
10 LHB 1 hits

Related Sentences

# PMID Sentence
1 2041484 Are syntax errors due to the amino acid sequence of neuroleukin involved in the pathogenesis of the acquired immunodeficiency syndrome (AIDS) and insulin dependent diabetes mellitus (IDDM)?
2 2041484 In AIDS the basic defect would be the human specific inability to distinguish between the amino acid sequence of neuroleukin and peptides derived from the gp120 envelope protein of HIV, resulting in a slowly progressing failure of the CD4+ T cell-mediated immunity.
3 2041484 In the ensuing dialogue neuroleukin secreted by T cells would imply a continuous demand for insulin secretion to pancreatic beta cells resulting in diabetes.
4 10336856 To investigate the role of our cloned transmembrane envelope protein in the pathogenesis of autoimmune insulin-dependent diabetes mellitus (IDDM) as an autoantigen or immunosuppressive modulator, a high amount of transmembrane envelope protein was essentially required.
5 10336856 The processed hydrophilic retroviral transmembrane envelope protein was still immune reactive with NOD sera and also showed immunosuppressive activity by down-regulating the Th1-type cytokine (interferon-gamma) and up-regulating the Th2-type cytokine (interleukin 10).
6 10336856 To investigate the role of our cloned transmembrane envelope protein in the pathogenesis of autoimmune insulin-dependent diabetes mellitus (IDDM) as an autoantigen or immunosuppressive modulator, a high amount of transmembrane envelope protein was essentially required.
7 10336856 The processed hydrophilic retroviral transmembrane envelope protein was still immune reactive with NOD sera and also showed immunosuppressive activity by down-regulating the Th1-type cytokine (interferon-gamma) and up-regulating the Th2-type cytokine (interleukin 10).
8 10942359 Human hematopoietic cell lines and cord blood-derived CD34(+) and CD34(+), CD38(-) cell populations and the progenitors contained therein were transduced far more efficiently with oncoretroviral particles pseudotyped with the envelope protein of feline endogenous virus (RD114) than with conventional amphotropic vector particles.
9 12719006 Furthermore, similar to earlier results with HIV gp120, CV-N bound with considerable affinity to the Ebola surface envelope glycoprotein, GP(1,2).
10 14645156 Autoantibodies and CD4 T cells target a beta cell retroviral envelope protein in non-obese diabetic mice.
11 16461228 Prolonged expression of the viral regulatory protein HBx and the large envelope protein LHBs may contribute in deregulating the cellular transcription program and proliferation control, and sensitize liver cells to carcinogenic factors.
12 16461228 By contrast, HBV related tumours harbour a low rate of beta-catenin mutations.