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Gene Information

Gene symbol: GADD45B

Gene name: growth arrest and DNA-damage-inducible, beta

HGNC ID: 4096

Synonyms: GADD45BETA, DKFZP566B133

Related Genes

#	Gene Symbol	Number of hits
1	GADD45A	1 hits
2	GADD45G	1 hits

Related Sentences

#	PMID	Sentence
1	16283526	Using Ikkbeta gene knockout mouse embryonic fibroblast cells (Ikkbeta-/-), in the present study we demonstrated that NF-kappaB inhibition due to Ikkbeta deficiency up-regulated basal and arsenic-induced expression of gadd45alpha.
2	16283526	In addition to gadd45alpha, the basal expression of other gadd family members including gadd45beta, gadd45gamma and gadd153 was substantially increased in Ikkbeta-/- cells.
3	16283526	Ikkbeta deficiency prevented the induction of gadd45beta and gadd45gamma by arsenic, whereas the induction of gadd45alpha and gadd153 was appreciably enhanced in Ikkbeta-/- cells.
4	16283526	Furthermore, a substantial decrease in the expression of c-myc, an established endogenous transcriptional repressor of gadd45alpha and gadd153 genes, was noted.
5	16283526	Using Ikkbeta gene knockout mouse embryonic fibroblast cells (Ikkbeta-/-), in the present study we demonstrated that NF-kappaB inhibition due to Ikkbeta deficiency up-regulated basal and arsenic-induced expression of gadd45alpha.
6	16283526	In addition to gadd45alpha, the basal expression of other gadd family members including gadd45beta, gadd45gamma and gadd153 was substantially increased in Ikkbeta-/- cells.
7	16283526	Ikkbeta deficiency prevented the induction of gadd45beta and gadd45gamma by arsenic, whereas the induction of gadd45alpha and gadd153 was appreciably enhanced in Ikkbeta-/- cells.
8	16283526	Furthermore, a substantial decrease in the expression of c-myc, an established endogenous transcriptional repressor of gadd45alpha and gadd153 genes, was noted.