- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: GCSH
Gene name:
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CYP2D6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9061564 | Levels of DM and its primary metabolite dextrorphan (DX) were utilized to guide DM therapy and exhibited patterns reflective of the extensive and poor metabolizer phenotypes for CYP2D6, the cytochrome P450 isoform responsible for DM metabolism. |
| 2 | 9061564 | In the patient who appeared to represent the extensive metabolizer (EM) phenotype, treatment with the non-specific cytochrome P450 inhibitor cimetidine was required to reduce biotransformation of DM to DX and, thus, to increase DM plasma concentrations. |
| 3 | 9061564 | These cases demonstrate the importance of CYP2D6 phenotype in providing safe and effective DM therapy to patients with NKH. |