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Gene Information

Gene symbol: GGA3

Gene name: golgi-associated, gamma adaptin ear containing, ARF binding protein 3

HGNC ID: 17079

Synonyms: KIAA0154

Related Genes

#	Gene Symbol	Number of hits
1	AP1G1	1 hits
2	RABEP1	1 hits
3	RPS27A	1 hits

Related Sentences

#	PMID	Sentence
1	12858162	Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3.
2	12858162	The gamma-adaptin ear (GAE) domains of the AP-1 adaptor protein complex and the GGA adaptor proteins recruit accessory proteins to these multiprotein complexes by binding to a hydrophobic motif.
3	12858162	We determined the structure of the GAE domain of human GGA3 in complex with a peptide based on the DFGPLV sequence of the accessory protein Rabaptin-5 and refined it at a resolution of 2.2 A.
4	12858162	Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3.
5	12858162	The gamma-adaptin ear (GAE) domains of the AP-1 adaptor protein complex and the GGA adaptor proteins recruit accessory proteins to these multiprotein complexes by binding to a hydrophobic motif.
6	12858162	We determined the structure of the GAE domain of human GGA3 in complex with a peptide based on the DFGPLV sequence of the accessory protein Rabaptin-5 and refined it at a resolution of 2.2 A.
7	15701688	Here we report the crystal structure of the GAT domain of human GGA3 in a 1:1 complex with ubiquitin at 2.8-A resolution.
8	15701688	The ubiquitin-binding site observed in the crystal is distinct from the Rabaptin-5-binding site on helices alpha2 and alpha3 of the GAT domain.
9	15701688	Mutational analysis and modeling of the ubiquitin-Rabaptin-5-GAT ternary complex indicates that ubiquitin and Rabaptin-5 can bind to the GAT domain at two different sites without any steric conflict.