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Gene Information
Gene symbol: GIF
Gene name: gastric intrinsic factor (vitamin B synthesis)
HGNC ID: 4268
Synonyms: TCN3, IF, IFMH, INF
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EDNRA | 1 hits |
| 2 | IL1B | 1 hits |
| 3 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17642242 | For evaluation of treatment with TNF inhibitors, RA patients should be determined for the ACR core set of measures, including tender joint count, swollen joint count, pain score, patient global assessment, physician global assessment, patient-reported functional disability, and acute phase reactants (ESR and CRP), and more practically for the 28-joint Disease Activity Score (DAS28) within the first 3-6 months, and the efficacy could be assessed using the ACR preliminary criteria and the EULAR criteria. |
| 2 | 17642242 | Post-marketing surveillance of INF and ETA in Japan indicated that the most serious adverse effects were bacterial pneumonia, pneumocytosis, and interstitial pneumonia, as well as tuberculosis. |
| 3 | 17642242 | So far no clinical predictors of response to TNF inhibitors have been identified, but genetic variation in the HLA-DRB1 and the LTA-TNF regions was shown to influence the response. |
| 4 | 20122988 | Confocal microscopy revealed abounden GPR30 expression in insulin, glucagon and somatostatin cells. |
| 5 | 20122988 | Dose-response studies of G-1 vs 17beta-estradiol in isolated islets at 1 or 12 mM glucose showed an almost identical pattern in that both compounds increased insulin and inhibited glucagon and somatostatin secretion. |
| 6 | 20122988 | ICI-182,780 and EM-652, potent antagonists of the 17beta-estradiol receptors (ER alpha and ER beta) did not influence the amplifying effect of G-1 or 17beta-estradiol on cAMP content or insulin secretion from isolated islets. |
| 7 | 20122988 | Cytokine-induced (IL-1 beta+TNFalpha+INF gamma) apoptosis in islets, cultured for 24h at 5mM glucose, was almost abolished by G-1 or 17beta-estradiol treatment. |