Ignet

Gene Information

Gene symbol: GLS2

Gene name: glutaminase 2 (liver, mitochondrial)

HGNC ID: 29570

Synonyms: GA, GLS, LGA, hLGA

Related Genes

#	Gene Symbol	Number of hits
1	AGA	1 hits
2	CS	1 hits
3	G6PD	1 hits
4	GAD1	1 hits
5	GHRL	1 hits
6	GLS	1 hits
7	GLUL	1 hits
8	H6PD	1 hits
9	IDH3B	1 hits
10	INS	1 hits
11	ME1	1 hits
12	PCK2	1 hits

Related Sentences

#	PMID	Sentence
1	1538831	Effect of starvation or streptozotocin-diabetes on phosphate-activated glutaminase of different rat brain regions.
2	1538831	Phosphate-activated glutaminase (PAG) was assayed in homogenates of brain cerebellum, hippocampus or striatum from normal, starved for 48 h to 120 h or streptozotocin-diabetic rats.
3	1538831	Effect of starvation or streptozotocin-diabetes on phosphate-activated glutaminase of different rat brain regions.
4	1538831	Phosphate-activated glutaminase (PAG) was assayed in homogenates of brain cerebellum, hippocampus or striatum from normal, starved for 48 h to 120 h or streptozotocin-diabetic rats.
5	2191954	Mammalian liver possesses a unique isozyme of phosphate-activated glutaminase which plays an important role in the regulation of glutamine catabolism.
6	2898738	Phosphate-activated glutaminase (PAG) and glutamic acid decarboxylase (GAD) were assayed in homogenates and synaptosomes obtained from starved (48 hr or 120 hr) and diabetic (streptozotocin) rat brain cortex.
7	3201971	LGA and AGA infants did not differ regarding instrumental deliveries or asphyxia.
8	3277537	A method for the purification of phosphate-activated glutaminase from the liver of streptozotocin-diabetic rats is described.
9	3473986	During prolonged (40-day) streptozotocin-diabetes in the rat there is a marked increase in both the size and the phosphate-activated glutaminase activity of the small intestine.
10	3569695	The maximal activity of phosphate-dependent glutaminase and glutamine metabolism in the colon and the small intestine of streptozotocin-diabetic rats.
11	3569695	The effects of short- and long-term diabetes on the maximal activities of phosphate-dependent glutaminase and glutamine metabolism were studied in the colon and the small intestine of streptozotocin-diabetic rats.
12	3569695	The maximal activity of colonic phosphate-dependent glutaminase was decreased [44% in mucosal scrapings (p less than 0.01); 29% in whole colon (p less than 0.001)] or unchanged in short- or long-term diabetes respectively.
13	3569695	The maximal activity of phosphate-dependent glutaminase and glutamine metabolism in the colon and the small intestine of streptozotocin-diabetic rats.
14	3569695	The effects of short- and long-term diabetes on the maximal activities of phosphate-dependent glutaminase and glutamine metabolism were studied in the colon and the small intestine of streptozotocin-diabetic rats.
15	3569695	The maximal activity of colonic phosphate-dependent glutaminase was decreased [44% in mucosal scrapings (p less than 0.01); 29% in whole colon (p less than 0.001)] or unchanged in short- or long-term diabetes respectively.
16	3569695	The maximal activity of phosphate-dependent glutaminase and glutamine metabolism in the colon and the small intestine of streptozotocin-diabetic rats.
17	3569695	The effects of short- and long-term diabetes on the maximal activities of phosphate-dependent glutaminase and glutamine metabolism were studied in the colon and the small intestine of streptozotocin-diabetic rats.
18	3569695	The maximal activity of colonic phosphate-dependent glutaminase was decreased [44% in mucosal scrapings (p less than 0.01); 29% in whole colon (p less than 0.001)] or unchanged in short- or long-term diabetes respectively.
19	6231975	Glutaminase I, glutamate dehydrogenase, glutamine synthetase, phosphoenolpyruvate carboxykinase (PEPCK), hexokinase, phosphofructokinase, fructose-1,6-diphosphatase, malate dehydrogenase, malic enzyme, and lactate dehydrogenase were measured.
20	6508757	The regulation of phosphate-activated glutaminase activity and glutamine metabolism in the streptozotocin-diabetic rat.
21	6508757	The activity of phosphate-activated glutaminase was increased in the kidney, liver and small intestine of rats made diabetic for 6 days with injection of streptozotocin (75 mg/kg body wt.).
22	6508757	The regulation of phosphate-activated glutaminase activity and glutamine metabolism in the streptozotocin-diabetic rat.
23	6508757	The activity of phosphate-activated glutaminase was increased in the kidney, liver and small intestine of rats made diabetic for 6 days with injection of streptozotocin (75 mg/kg body wt.).
24	8174761	Liver possesses a unique isozyme of phosphate activated glutaminase which is subject to long-term regulation. 2.
25	8262331	In the liver, glutamine is hydrolyzed by a unique liver-type, phosphate-activated glutaminase, and the end products of hepatic glutamine catabolism are glucose and urea.
26	8930799	We hypothesize that in large for gestational age (LGA) infants, insulin-sensitive tissue will demonstrate the greatest accelerated growth.
27	11533295	Mechanisms governing the expression of the enzymes of glutamine metabolism--glutaminase and glutamine synthetase.
28	11533295	Whether on the scale of a single cell, organ or organism, glutamine homeostasis is to a large extent determined by the activities of glutaminase (GA, EC 3.5.1.2) and glutamine synthetase (GS, EC 6.3.1.2), the two enzymes that are the focus of this report.
29	12098663	The activities of hexokinase, phosphofructokinase, glucose-6-phosphate dehydrogenase (G6PDH), citrate synthase and phosphate-dependent glutaminase were determined.
30	12098663	The activities of hexokinase, G6PDH and citrate synthase were decreased by the diabetic state, whereas that of phosphofructokinase was raised.
31	12970305	We measured ghrelin in small (SGA), appropriate (AGA), and large (LGA) for gestational age neonates and evaluated whether ghrelin levels are modulated by neonatal insulin and glucose concentrations.
32	12970305	Plasma concentrations of ghrelin, insulin, and glucose were measured in cord blood sampled at birth in 123 SGA, AGA, and LGA neonates (gestational age, 24-41 wk) born to mothers with and without diabetes.
33	13129678	The difference between AGA- and LGA-diabetic placentae was related to relative placental weight and our data suggest that an increase in relative weight may protect the fetus from asphyxia.
34	16461555	The activities of hexokinase, glucose-6-phosphate dehydrogenase (G6PDH), phosphofructokinase (PFK), citrate synthase, phosphate-dependent glutaminase, NAD+-linked and NADP+-linked isocitrate dehydrogenase were assayed.
35	16461555	The activities of G6PDH and glutaminase were decreased, whereas that of PFK was raised by the diabetic state.