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Gene Information
Gene symbol: GPC2
Gene name:
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GPC3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11454708 | In contrast, the expression of glypican-3 and -4 is only slightly increased in breast cancers by comparison with normal breast tissues, and glypican-2 and -5 are below the level of detection by Northern blotting in both normal and cancer samples. |
| 2 | 11454708 | Treatment of MDA-MB-231 and MDA-MB-468 breast cancer cells with phosphoinositide-specific phospholipase-C abrogated the mitogenic response to two heparin-binding growth factors, heparin-binding epidermal growth factor-like growth factor and fibroblast growth factor 2. |
| 3 | 11454708 | Stable transfection of these cells with a glypican-1 antisense construct markedly decreased glypican-1 protein levels and the mitogenic response to the same heparin-binding growth factors, as well as that to heregulin alpha, heregulin beta, and hepatocyte growth factor. |
| 4 | 11454708 | There was a good correlation between glypican-1 and syndecan-1 expression in the tumors. |
| 5 | 11454708 | However, clones expressing the glypican-1 antisense construct did not exhibit decreased syndecan-1 levels, indicating that loss of responsiveness to heparin-binding growth factors in these clones was not due to altered syndecan-1 expression. |