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Gene Information

Gene symbol: GPR109B

Gene name: G protein-coupled receptor 109B

HGNC ID: 16824

Related Genes

# Gene Symbol Number of hits
1 CCRK 1 hits
2 GPBAR1 1 hits
3 GPR109A 1 hits
4 IFI44 1 hits
5 MAPK1 1 hits
6 MAPK3 1 hits

Related Sentences

# PMID Sentence
1 16389067 Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74.
2 16389067 Recently, two G protein-coupled receptors (GPCRs) for niacin were identified and characterized as high (HM74A; GPR109A) and low (HM74; GPR109B) affinity receptors based on the binding affinities of niacin.
3 16389067 Constructs expressing HM74A or HM74 were stably transfected into CHO-K1 cells and shown to elicit phosphorylation of p42 and p44 mitogen-activated protein kinase (ERK1/ERK2) phosphorylation upon addition of niacin or acifran.
4 16389067 The presence of functionally coupled GPCRs was further confirmed using Pertussis toxin, which completely inhibited the ability of either niacin or acifran to elicit phospho-ERK1/ERK2.
5 16389067 Two chemical analogs of acifran demonstrated robust phosphorylation of ERK1/ERK2.
6 16389067 Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74.
7 16389067 Recently, two G protein-coupled receptors (GPCRs) for niacin were identified and characterized as high (HM74A; GPR109A) and low (HM74; GPR109B) affinity receptors based on the binding affinities of niacin.
8 16389067 Constructs expressing HM74A or HM74 were stably transfected into CHO-K1 cells and shown to elicit phosphorylation of p42 and p44 mitogen-activated protein kinase (ERK1/ERK2) phosphorylation upon addition of niacin or acifran.
9 16389067 The presence of functionally coupled GPCRs was further confirmed using Pertussis toxin, which completely inhibited the ability of either niacin or acifran to elicit phospho-ERK1/ERK2.
10 16389067 Two chemical analogs of acifran demonstrated robust phosphorylation of ERK1/ERK2.
11 16389067 Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74.
12 16389067 Recently, two G protein-coupled receptors (GPCRs) for niacin were identified and characterized as high (HM74A; GPR109A) and low (HM74; GPR109B) affinity receptors based on the binding affinities of niacin.
13 16389067 Constructs expressing HM74A or HM74 were stably transfected into CHO-K1 cells and shown to elicit phosphorylation of p42 and p44 mitogen-activated protein kinase (ERK1/ERK2) phosphorylation upon addition of niacin or acifran.
14 16389067 The presence of functionally coupled GPCRs was further confirmed using Pertussis toxin, which completely inhibited the ability of either niacin or acifran to elicit phospho-ERK1/ERK2.
15 16389067 Two chemical analogs of acifran demonstrated robust phosphorylation of ERK1/ERK2.