Ignet

Gene Information

Gene symbol: GPT2

Gene name: glutamic pyruvate transaminase (alanine aminotransferase) 2

HGNC ID: 18062

Synonyms: ALT2

Related Genes

#	Gene Symbol	Number of hits
1	ALPI	1 hits
2	GGT1	1 hits
3	GPT	1 hits

Related Sentences

#	PMID	Sentence
1	11863375	In this study, we cloned a homolog of GPT and named it GPT2, and the corresponding protein ALT2.
2	11863375	GPT2 shares 69% identity and 78% similarity at the protein level to the previously cloned GPT.
3	11863375	GPT2 and GPT differ in mRNA expression in that GPT2 is highly expressed in muscle, fat, and kidney, whereas GPT is mainly expressed in kidney, liver, and heart.
4	11863375	In addition, GPT2 seems to be the predominant form of GPT at the mRNA level in these tissues.
5	11863375	The more abundant expression of GPT2 than GPT, especially in muscle and fat, suggests a unique and previously unrecognized role of this gene product in glucose, amino acid, and fatty acid metabolism and homeostasis.
6	11863375	In this study, we cloned a homolog of GPT and named it GPT2, and the corresponding protein ALT2.
7	11863375	GPT2 shares 69% identity and 78% similarity at the protein level to the previously cloned GPT.
8	11863375	GPT2 and GPT differ in mRNA expression in that GPT2 is highly expressed in muscle, fat, and kidney, whereas GPT is mainly expressed in kidney, liver, and heart.
9	11863375	In addition, GPT2 seems to be the predominant form of GPT at the mRNA level in these tissues.
10	11863375	The more abundant expression of GPT2 than GPT, especially in muscle and fat, suggests a unique and previously unrecognized role of this gene product in glucose, amino acid, and fatty acid metabolism and homeostasis.
11	11863375	In this study, we cloned a homolog of GPT and named it GPT2, and the corresponding protein ALT2.
12	11863375	GPT2 shares 69% identity and 78% similarity at the protein level to the previously cloned GPT.
13	11863375	GPT2 and GPT differ in mRNA expression in that GPT2 is highly expressed in muscle, fat, and kidney, whereas GPT is mainly expressed in kidney, liver, and heart.
14	11863375	In addition, GPT2 seems to be the predominant form of GPT at the mRNA level in these tissues.
15	11863375	The more abundant expression of GPT2 than GPT, especially in muscle and fat, suggests a unique and previously unrecognized role of this gene product in glucose, amino acid, and fatty acid metabolism and homeostasis.
16	11863375	In this study, we cloned a homolog of GPT and named it GPT2, and the corresponding protein ALT2.
17	11863375	GPT2 shares 69% identity and 78% similarity at the protein level to the previously cloned GPT.
18	11863375	GPT2 and GPT differ in mRNA expression in that GPT2 is highly expressed in muscle, fat, and kidney, whereas GPT is mainly expressed in kidney, liver, and heart.
19	11863375	In addition, GPT2 seems to be the predominant form of GPT at the mRNA level in these tissues.
20	11863375	The more abundant expression of GPT2 than GPT, especially in muscle and fat, suggests a unique and previously unrecognized role of this gene product in glucose, amino acid, and fatty acid metabolism and homeostasis.
21	11863375	In this study, we cloned a homolog of GPT and named it GPT2, and the corresponding protein ALT2.
22	11863375	GPT2 shares 69% identity and 78% similarity at the protein level to the previously cloned GPT.
23	11863375	GPT2 and GPT differ in mRNA expression in that GPT2 is highly expressed in muscle, fat, and kidney, whereas GPT is mainly expressed in kidney, liver, and heart.
24	11863375	In addition, GPT2 seems to be the predominant form of GPT at the mRNA level in these tissues.
25	11863375	The more abundant expression of GPT2 than GPT, especially in muscle and fat, suggests a unique and previously unrecognized role of this gene product in glucose, amino acid, and fatty acid metabolism and homeostasis.
26	15122758	In this study, we have cloned the complementary DNAs of murine homologues of human alanine aminotransferase 1 and 2 (ALT1 and ALT2).
27	15122758	The deduced peptides of murine ALT1 (mALT1) and ALT2 (mALT2) share 87% and 93% identity, respectively, with their human counterparts at the amino acid level.
28	15122758	Murine ALT genes localize to separate chromosomes, with mALT1 gene (gpt1) on chromosome 15 and mALT2 gene (gpt2) on chromosome 8.
29	15122758	Expression of recombinant mALT1 and mALT2 proteins in Escherichia coli (E. coli) produced functional enzymes that catalyze alanine transamination.
30	15122758	In fatty livers of obese mice, ALT2 gene expression is induced 2-fold, but ALT1 remains the same.
31	15122758	In this study, we have cloned the complementary DNAs of murine homologues of human alanine aminotransferase 1 and 2 (ALT1 and ALT2).
32	15122758	The deduced peptides of murine ALT1 (mALT1) and ALT2 (mALT2) share 87% and 93% identity, respectively, with their human counterparts at the amino acid level.
33	15122758	Murine ALT genes localize to separate chromosomes, with mALT1 gene (gpt1) on chromosome 15 and mALT2 gene (gpt2) on chromosome 8.
34	15122758	Expression of recombinant mALT1 and mALT2 proteins in Escherichia coli (E. coli) produced functional enzymes that catalyze alanine transamination.
35	15122758	In fatty livers of obese mice, ALT2 gene expression is induced 2-fold, but ALT1 remains the same.
36	15122758	In this study, we have cloned the complementary DNAs of murine homologues of human alanine aminotransferase 1 and 2 (ALT1 and ALT2).
37	15122758	The deduced peptides of murine ALT1 (mALT1) and ALT2 (mALT2) share 87% and 93% identity, respectively, with their human counterparts at the amino acid level.
38	15122758	Murine ALT genes localize to separate chromosomes, with mALT1 gene (gpt1) on chromosome 15 and mALT2 gene (gpt2) on chromosome 8.
39	15122758	Expression of recombinant mALT1 and mALT2 proteins in Escherichia coli (E. coli) produced functional enzymes that catalyze alanine transamination.
40	15122758	In fatty livers of obese mice, ALT2 gene expression is induced 2-fold, but ALT1 remains the same.
41	15122758	In this study, we have cloned the complementary DNAs of murine homologues of human alanine aminotransferase 1 and 2 (ALT1 and ALT2).
42	15122758	The deduced peptides of murine ALT1 (mALT1) and ALT2 (mALT2) share 87% and 93% identity, respectively, with their human counterparts at the amino acid level.
43	15122758	Murine ALT genes localize to separate chromosomes, with mALT1 gene (gpt1) on chromosome 15 and mALT2 gene (gpt2) on chromosome 8.
44	15122758	Expression of recombinant mALT1 and mALT2 proteins in Escherichia coli (E. coli) produced functional enzymes that catalyze alanine transamination.
45	15122758	In fatty livers of obese mice, ALT2 gene expression is induced 2-fold, but ALT1 remains the same.
46	15122758	In this study, we have cloned the complementary DNAs of murine homologues of human alanine aminotransferase 1 and 2 (ALT1 and ALT2).
47	15122758	The deduced peptides of murine ALT1 (mALT1) and ALT2 (mALT2) share 87% and 93% identity, respectively, with their human counterparts at the amino acid level.
48	15122758	Murine ALT genes localize to separate chromosomes, with mALT1 gene (gpt1) on chromosome 15 and mALT2 gene (gpt2) on chromosome 8.
49	15122758	Expression of recombinant mALT1 and mALT2 proteins in Escherichia coli (E. coli) produced functional enzymes that catalyze alanine transamination.
50	15122758	In fatty livers of obese mice, ALT2 gene expression is induced 2-fold, but ALT1 remains the same.
51	21534331	Alkaline phosphatase was 24-fold upper limit of normal (ULN), gamma-glutamyl transpeptidase 21-fold ULN, aspartate aminotransferase 3-fold ULN, alanine aminotransferase 2-fold ULN, cholesterol 408 mg/dL, bilirubin normal, gamma-globulin 3.92 g/dL, IgG4 4.6 g/L, antinuclear antibody positive (1/320), and antimitochondrial antibodies negative.