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PMID |
Sentence |
1 |
11755899
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At various time intervals after induction of diabetes the neurons in the paraventricular- (PVN) and supraoptic- (SON) nucleus showed upregulated arginine vasopressin (AVP) and oxytocin (OXT) immunoexpression, being most pronounced at 2 weeks.
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2 |
11755899
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This is coupled by upregulation of NMDAR1 and nNOS but downregulation of GluR2/3.
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3 |
18220716
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Activation of group-II (mGluR2 and -3) or group-III metabotropic glutamate receptors (mGluR4, -6, -7 and -8) has been established to be neuroprotective in vitro and in vivo.
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4 |
18220716
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In contrast, group-I mGluRs (mGluR1 and -5) need to be antagonized in order to evoke protection.
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5 |
18258217
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Immunohistochemical analysis was performed using specific antibodies directed against the ionotropic alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionate (AMPA) receptor subunits GluR1, GluR2, GluR4, and against the N-methyl-d-aspartate glutamate receptor subunit NR1.
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6 |
18258217
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In the inner plexiform and outer plexiform layers the immunoreactivity of GluR2 and NR1 subunits was significantly increased in subjects with diabetes when compared to the levels found in controls.
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7 |
18258217
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No significant changes in GluR1 and GluR4 subunit expression were observed.
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8 |
18258217
|
Immunohistochemical analysis was performed using specific antibodies directed against the ionotropic alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionate (AMPA) receptor subunits GluR1, GluR2, GluR4, and against the N-methyl-d-aspartate glutamate receptor subunit NR1.
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9 |
18258217
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In the inner plexiform and outer plexiform layers the immunoreactivity of GluR2 and NR1 subunits was significantly increased in subjects with diabetes when compared to the levels found in controls.
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10 |
18258217
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No significant changes in GluR1 and GluR4 subunit expression were observed.
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