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Gene Information

Gene symbol: GRIA4

Gene name: glutamate receptor, ionotropic, AMPA 4

HGNC ID: 4574

Synonyms: GluA4, GLURD

Related Genes

# Gene Symbol Number of hits
1 GRIA1 1 hits
2 GRIA2 1 hits
3 GRIN1 1 hits
4 GRM3 1 hits
5 GRM4 1 hits
6 GRM8 1 hits

Related Sentences

# PMID Sentence
1 15047615 RT-PCR and immunological analyses indicated that mGluR4, a class III mGluR, was expressed and localized with alpha- and F cells, whereas no evidence for expression of other mGluRs, including mGluR8, was obtained.
2 15220198 A novel variant of ionotropic glutamate receptor regulates somatostatin secretion from delta-cells of islets of Langerhans.
3 15220198 Somatostatin from delta-cells, considered a local inhibitor of islet function, reduces insulin and glucagon secretion by activating somatostatin receptors in islet cells.
4 15220198 Somatostatin secretion from delta-cells is increased by high glucose via glucose metabolism in a similar way to insulin secretion from beta-cells.
5 15220198 In this study, we showed that delta-cells express GluR4c-flip, a newly identified splicing variant of GluR4, an (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type ionotropic glutamate receptor of rat.
6 18220716 Activation of group-II (mGluR2 and -3) or group-III metabotropic glutamate receptors (mGluR4, -6, -7 and -8) has been established to be neuroprotective in vitro and in vivo.
7 18220716 In contrast, group-I mGluRs (mGluR1 and -5) need to be antagonized in order to evoke protection.
8 18258217 Immunohistochemical analysis was performed using specific antibodies directed against the ionotropic alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionate (AMPA) receptor subunits GluR1, GluR2, GluR4, and against the N-methyl-d-aspartate glutamate receptor subunit NR1.
9 18258217 In the inner plexiform and outer plexiform layers the immunoreactivity of GluR2 and NR1 subunits was significantly increased in subjects with diabetes when compared to the levels found in controls.
10 18258217 No significant changes in GluR1 and GluR4 subunit expression were observed.
11 18258217 Immunohistochemical analysis was performed using specific antibodies directed against the ionotropic alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionate (AMPA) receptor subunits GluR1, GluR2, GluR4, and against the N-methyl-d-aspartate glutamate receptor subunit NR1.
12 18258217 In the inner plexiform and outer plexiform layers the immunoreactivity of GluR2 and NR1 subunits was significantly increased in subjects with diabetes when compared to the levels found in controls.
13 18258217 No significant changes in GluR1 and GluR4 subunit expression were observed.
14 22506633 Metabotropic glutamate receptor 4 (mGlu4)-positive allosteric modulators for the treatment of Parkinson's disease: historical perspective and review of the patent literature.