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Gene Information
Gene symbol: HAS3
Gene name: hyaluronan synthase 3
HGNC ID: 4820
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HAS1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16733556 | The involvement of transforming growth factor beta1 and its activation by thrombospondin-1. |
| 2 | 16733556 | The cause of the increased high-molecular-weight HA synthesis consisted in the up-regulation of hyaluronan synthase (HAS) 2 mRNA without alterations of the expression of HAS3, which generates HA of lower molecular weight. |
| 3 | 16733556 | D-Glucose at 30 mM also stimulated the production of transforming growth factor beta1 (TGFbeta1), the excessive activation of which was determined by the up-regulation of thrombospondin-1 (TSP-1). |
| 4 | 16733556 | The blockage of TGFbeta1 action either by neutralizing anti-TGFbeta1 antibodies or by quenching the TGFbeta1 activation (with TSP-1-derived synthetic GGWSHW peptide) abolished the effect of high glucose on HAS2 mRNA expression and normalized the synthesis of HA. |