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Gene Information
Gene symbol: HIST1H2AA
Gene name: histone cluster 1, H2aa
HGNC ID: 18729
Synonyms: bA317E16.2, H2AFR
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
18793623
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Morin was found to prevent the cellular DNA damage induced by H(2)O(2) treatment, which is shown by the inhibition of 8-hydroxy-2'-deoxyguanosine (8-OHdG) formation (a modified form of DNA base), inhibition of comet tail (a form of DNA strand breakage), and decrease of nuclear phospho histone H2A.X expression (a marker for DNA strand breakage).
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2 |
19164757
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Like bortezomib, EerI-induced cytotoxicity requires the up-regulation of the Bcl-2 homology3 (BH3)-only pro-apoptotic protein NOXA.
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3 |
19164757
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First, these agents elicit an integrated stress response program at the ER to activate the CREB/ATF transcription factors ATF3 and ATF4.
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4 |
19164757
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We show that ATF3 and ATF4 form a complex capable of binding to the NOXA promoter, which is required for NOXA activation.
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5 |
19164757
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Second, EerI and bortezomib also block ubiquitination of histone H2A to relieve its inhibition on NOXA transcription.
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6 |
23738337
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Impact of high glucose and proteasome inhibitor MG132 on histone H2A and H2B ubiquitination in rat glomerular mesangial cells.
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