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Gene Information
Gene symbol: HIST2H2AC
Gene name: histone cluster 2, H2ac
HGNC ID: 4738
Synonyms: H2A/q
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | H2AFX | 1 hits |
| 2 | H2AFY | 1 hits |
| 3 | HIST1H2AA | 1 hits |
| 4 | HIST2H2BE | 1 hits |
| 5 | OGT | 1 hits |
| 6 | PMAIP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 1990277 | Changes in the structure of this active chromatin dependent on the presence of exogeneous Mg2+ ATP or on the addition of a mixture of histones H2A and H2B are shown to lead to the selective repression of Xenopus 5S RNA genes. |
| 2 | 9372946 | Histone octamers consisting of H2A, H2B, H3, and H4 are reconstituted onto DNA duplexes containing an artificial nucleosome-positioning sequence consisting of a tandem array of an alternating AT-GC sequence motif. |
| 3 | 17575053 | We report here that H3.3 nucleosomes isolated from vertebrates, regardless of whether they are partnered with H2A or H2A.Z, are unusually sensitive to salt-dependent disruption, losing H2A/H2B or H2A.Z/H2B dimers. |
| 4 | 19164757 | Like bortezomib, EerI-induced cytotoxicity requires the up-regulation of the Bcl-2 homology3 (BH3)-only pro-apoptotic protein NOXA. |
| 5 | 19164757 | First, these agents elicit an integrated stress response program at the ER to activate the CREB/ATF transcription factors ATF3 and ATF4. |
| 6 | 19164757 | We show that ATF3 and ATF4 form a complex capable of binding to the NOXA promoter, which is required for NOXA activation. |
| 7 | 19164757 | Second, EerI and bortezomib also block ubiquitination of histone H2A to relieve its inhibition on NOXA transcription. |
| 8 | 20372103 | An early response to the induction of DSBs is phosphorylation of the H2A histone variant, H2AX, at the serine-139 residue, in the highly conserved C-terminal SQEY motif, forming gammaH2AX(1). |
| 9 | 20372103 | Following induction of DSBs, H2AX is rapidly phosphorylated by the phosphatidyl-inosito 3-kinase (PIKK) family of proteins, ataxia telangiectasia mutated (ATM), DNA-protein kinase catalytic subunit and ATM and RAD3-related (ATR)(2). |
| 10 | 20372103 | Phosphorylation of H2AX mediated predominantly by ATM spreads to adjacent areas of chromatin, affecting approximately 0.03% of total cellular H2AX per DSB(2,3). |
| 11 | 20613712 | Phosphorylation of the H2A histone variant, H2AX, at the serine-139 residue, in the highly conserved C-terminal SQEY motif, forming gammaH2AX, is an early response to DNA double-strand breaks. |
| 12 | 20613712 | This phosphorylation event is mediated by the phosphatidyl-inosito 3-kinase (PI3K) family of proteins, ataxia telangiectasia mutated (ATM), DNA-protein kinase catalytic subunit and ATM and RAD3-related (ATR). |
| 13 | 21249133 | Three of the found H2A potentially organize small nucleosomes in transcriptionally active chromatin, while two H2AFY variants inactivate X chromosome in female cells. |
| 14 | 21249133 | H2AFX and H2AFY revealed differential and variable N-terminal processing. |
| 15 | 22371497 | A recent study also found that all four core nucleosomal histones (H2A, H2B, H3, and H4) are modified with O-GlcNAc, although no specific sites on H3 were reported. |
| 16 | 23738337 | Impact of high glucose and proteasome inhibitor MG132 on histone H2A and H2B ubiquitination in rat glomerular mesangial cells. |