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Gene Information
Gene symbol: HORMAD2
Gene name:
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HLA-DPB2 | 1 hits |
| 2 | HLA-DQB1 | 1 hits |
| 3 | HLA-DRB1 | 1 hits |
| 4 | PSMB9 | 1 hits |
| 5 | TAP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22737082 | In a recent GWAS, we localized five IgAN susceptibility loci on Chr.6p21 (HLA-DQB1/DRB1, PSMB9/TAP1, and DPA1/DPB2 loci), Chr.1q32 (CFHR3/R1 locus), and Chr.22q12 (HORMAD2 locus). |
| 2 | 22737082 | Four susceptibility loci robustly replicated and all five loci were genome-wide significant in the combined cohort (P = 5×10⁻³²-3×10⁻¹⁰), with heterogeneity detected only at the PSMB9/TAP1 locus (I² = 0.60). |
| 3 | 22737082 | Conditional analyses identified two new independent risk alleles within the HLA-DQB1/DRB1 locus, defining multiple risk and protective haplotypes within this interval. |