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PMID |
Sentence |
1 |
12759458
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IFN-kappa belongs to a recently identified subclass of type I IFNs.
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12759458
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Murine IFN-kappa contains four cysteines in analogous positions to those observed in the IFN-alpha and an additional fifth unique cysteine, C174.
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3 |
12759458
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The murine gene is located on chromosome 4, where other type I murine IFN genes, IFN-alpha and IFN-beta, are clustered.
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4 |
12759458
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This region is syntenic with human chromosome 9 where the gene encoding IFN-kappa and the type I IFN gene cluster are found.
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5 |
12759458
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Mouse IFN-kappa is expressed at low levels in peritoneal macrophages and its expression is up-regulated by dsRNA and IFN-gamma.
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6 |
12759458
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Similar to previously reported transgenic mice carrying type I and type II IFNs, transgenic mice overexpressing murine IFN-kappa in the beta cells of the pancreas develop overt diabetes with hyperglycemia.
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7 |
12759458
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IFN-kappa belongs to a recently identified subclass of type I IFNs.
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8 |
12759458
|
Murine IFN-kappa contains four cysteines in analogous positions to those observed in the IFN-alpha and an additional fifth unique cysteine, C174.
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9 |
12759458
|
The murine gene is located on chromosome 4, where other type I murine IFN genes, IFN-alpha and IFN-beta, are clustered.
|
10 |
12759458
|
This region is syntenic with human chromosome 9 where the gene encoding IFN-kappa and the type I IFN gene cluster are found.
|
11 |
12759458
|
Mouse IFN-kappa is expressed at low levels in peritoneal macrophages and its expression is up-regulated by dsRNA and IFN-gamma.
|
12 |
12759458
|
Similar to previously reported transgenic mice carrying type I and type II IFNs, transgenic mice overexpressing murine IFN-kappa in the beta cells of the pancreas develop overt diabetes with hyperglycemia.
|
13 |
12759458
|
IFN-kappa belongs to a recently identified subclass of type I IFNs.
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14 |
12759458
|
Murine IFN-kappa contains four cysteines in analogous positions to those observed in the IFN-alpha and an additional fifth unique cysteine, C174.
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15 |
12759458
|
The murine gene is located on chromosome 4, where other type I murine IFN genes, IFN-alpha and IFN-beta, are clustered.
|
16 |
12759458
|
This region is syntenic with human chromosome 9 where the gene encoding IFN-kappa and the type I IFN gene cluster are found.
|
17 |
12759458
|
Mouse IFN-kappa is expressed at low levels in peritoneal macrophages and its expression is up-regulated by dsRNA and IFN-gamma.
|
18 |
12759458
|
Similar to previously reported transgenic mice carrying type I and type II IFNs, transgenic mice overexpressing murine IFN-kappa in the beta cells of the pancreas develop overt diabetes with hyperglycemia.
|
19 |
12759458
|
IFN-kappa belongs to a recently identified subclass of type I IFNs.
|
20 |
12759458
|
Murine IFN-kappa contains four cysteines in analogous positions to those observed in the IFN-alpha and an additional fifth unique cysteine, C174.
|
21 |
12759458
|
The murine gene is located on chromosome 4, where other type I murine IFN genes, IFN-alpha and IFN-beta, are clustered.
|
22 |
12759458
|
This region is syntenic with human chromosome 9 where the gene encoding IFN-kappa and the type I IFN gene cluster are found.
|
23 |
12759458
|
Mouse IFN-kappa is expressed at low levels in peritoneal macrophages and its expression is up-regulated by dsRNA and IFN-gamma.
|
24 |
12759458
|
Similar to previously reported transgenic mice carrying type I and type II IFNs, transgenic mice overexpressing murine IFN-kappa in the beta cells of the pancreas develop overt diabetes with hyperglycemia.
|
25 |
12759458
|
IFN-kappa belongs to a recently identified subclass of type I IFNs.
|
26 |
12759458
|
Murine IFN-kappa contains four cysteines in analogous positions to those observed in the IFN-alpha and an additional fifth unique cysteine, C174.
|
27 |
12759458
|
The murine gene is located on chromosome 4, where other type I murine IFN genes, IFN-alpha and IFN-beta, are clustered.
|
28 |
12759458
|
This region is syntenic with human chromosome 9 where the gene encoding IFN-kappa and the type I IFN gene cluster are found.
|
29 |
12759458
|
Mouse IFN-kappa is expressed at low levels in peritoneal macrophages and its expression is up-regulated by dsRNA and IFN-gamma.
|
30 |
12759458
|
Similar to previously reported transgenic mice carrying type I and type II IFNs, transgenic mice overexpressing murine IFN-kappa in the beta cells of the pancreas develop overt diabetes with hyperglycemia.
|