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Gene Information
Gene symbol: IGKV6-21
Gene name: immunoglobulin kappa variable 6-21
HGNC ID: 5836
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | C21orf63 | 1 hits |
| 2 | HPT | 1 hits |
| 3 | IDDM2 | 1 hits |
| 4 | IGKV1-22 | 1 hits |
| 5 | IGKV2-23 | 1 hits |
| 6 | MRAP | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 3496374 | Primary hypoparathyroidism and hypogonadism were present in each, adrenal insufficiency in two, and insulin-dependent diabetes mellitus and latent hypothyroidism in single subjects. |
| 2 | 3496374 | HLA A26 or A25 were present in all seven. |
| 3 | 6944299 | On the other hand, the frequency of A26, B18, and Bw38 was increased in Ashkenazi patients, but not in non-Ashkenazim, who in turn showed an increase for Bw51. |
| 4 | 6944299 | There was a typical excess of DR3/DR4 heterozygotes in both patient groups. |
| 5 | 8977763 | Hypoparathyroidism and insulin-dependent diabetes mellitus in a patient with Kearns-Sayre syndrome harbouring a mitochondrial DNA deletion. |
| 6 | 8977763 | She also had insulin-dependent diabetes mellitus (IDDM). |
| 7 | 8977763 | Human leucocyte associated antigen typing showed A24, A26; B54, B61; CW1, CW3; DR8, DR14; DQ1 and DQ3, suggesting that the presence of HLA-A24 and CW3 antigen contributed to the association of IDDM and hypoparathyroidism, similar to Japanese patients with polyglandular autoimmune syndrome, complicated by hypoparathyroidism and IDDM. |
| 8 | 8977763 | This is an extremely rare case of Kearns-Sayre syndrome, presenting in association with IDDM and idiopathic hypoparathyroidism. |
| 9 | 12621776 | Age, DM in family, CMV infections, genetic factor (HLA A26 and B27), immunosuppressive treatment with steroids or calcineurin inhibitors belong to the major risk factors of diabetes. |