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Gene Information

Gene symbol: IL18R1

Gene name: interleukin 18 receptor 1

HGNC ID: 5988

Synonyms: IL1RRP, IL-1Rrp, CD218a

Related Genes

# Gene Symbol Number of hits
1 IL18 1 hits

Related Sentences

# PMID Sentence
1 17075045 By neutralizing IL-18 activity with IL-18 binding protein (IL-18BP), we observed that islets produce bioactive IL-18.
2 17075045 In related studies, IL-18R-deficient splenocytes and macrophages produced 2- to 3-fold greater amounts of IL-18, TNFalpha, macrophage inflammatory protein 1, macrophage inflammatory protein 2, and IFNgamma upon stimulation with Con A, Toll-like receptor 2 agonist, or anti-CD3 antibodies.
3 17075045 Importantly, discrepancies between IL-18- and IL-18R-deficient cells suggest that IL-18Ralpha chain is used by an inflammation-suppressing signal.