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Gene Information
Gene symbol: IL18R1
Gene name: interleukin 18 receptor 1
HGNC ID: 5988
Synonyms: IL1RRP, IL-1Rrp, CD218a
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
17075045
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By neutralizing IL-18 activity with IL-18 binding protein (IL-18BP), we observed that islets produce bioactive IL-18.
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2 |
17075045
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In related studies, IL-18R-deficient splenocytes and macrophages produced 2- to 3-fold greater amounts of IL-18, TNFalpha, macrophage inflammatory protein 1, macrophage inflammatory protein 2, and IFNgamma upon stimulation with Con A, Toll-like receptor 2 agonist, or anti-CD3 antibodies.
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3 |
17075045
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Importantly, discrepancies between IL-18- and IL-18R-deficient cells suggest that IL-18Ralpha chain is used by an inflammation-suppressing signal.
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