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Gene Information
Gene symbol: INPP5A
Gene name:
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GAD1 | 1 hits |
| 2 | IPPK | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9342546 | All 10 displayed 37/40kD and/or GAD antibodies during the prediabetic phase. |
| 2 | 9887080 | Renal type I inositol 1,4,5-trisphosphate receptor is reduced in streptozotocin-induced diabetic rats and mice. |
| 3 | 9887080 | We have previously demonstrated that the cytokine transforming growth factor-beta1 (TGF-beta1) is increased in early diabetic kidney disease and TGF-beta1 inhibits the expression of the inositol 1,4,5-trisphosphate (IP3)-gated calcium channel, the type I IP3 receptor (IP3R), in mesangial cells. |
| 4 | 9887080 | Reduction of type I IP3R also occurred in parallel with renal hypertrophy, increased creatinine clearance, and increased renal TGF-beta1 expression in the diabetic rats. |
| 5 | 9887080 | Two-week-old diabetic mice also had reduced renal type I IP3R protein and mRNA expression in association with renal hypertrophy and increased TGF-beta1 mRNA expression. |