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Gene Information
Gene symbol: IRF9
Gene name: interferon regulatory factor 9
HGNC ID: 6131
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BHLHB8 | 1 hits |
| 2 | INS | 1 hits |
| 3 | ISL1 | 1 hits |
| 4 | NEUROD1 | 1 hits |
| 5 | NKX2-2 | 1 hits |
| 6 | NKX6-1 | 1 hits |
| 7 | NKX6-2 | 1 hits |
| 8 | PAX4 | 1 hits |
| 9 | PDX1 | 1 hits |
| 10 | PTF1A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10377278 | Transcription factors such as Pdx1, p48 and Nkx2.2 have been shown to be essential for the proper differentiation of exocrine and endocrine tissue; however, pancreas development also involves intricate interactions between the pancreatic epithelium and its surrounding mesenchyme. |
| 2 | 17003479 | We demonstrate that under these experimental conditions the exocrine acinar cells lose their differentiated characteristics: expression of the acinar transcription factors p48/Ptf1alpha and Mist1 is decreased or lost, whereas expression of the embryonic transcription factor Pdx1 is increased. |
| 3 | 17003479 | The receptors Notch1 and Notch2, members of the DSL family of Notch ligands, and the target genes in the Notch-signaling pathway Hes1, Hey1, and Hey2 become strongly up-regulated. |
| 4 | 17003479 | This effect seems to be Hes1-independent and mainly coincides with decreased Hey1 and Hey2 mRNA expression. |
| 5 | 17009890 | PPlike cells show a strong upregulation of Ipf1/Pdx1, p48, Isl-1 and Nkx6.1, but not Ngn3, NeuroD/ Beta2 or Pax4. |
| 6 | 23471885 | Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male mice. |