Ignet

Gene Information

Gene symbol: KCNK3

Gene name: potassium channel, subfamily K, member 3

HGNC ID: 6278

Synonyms: K2p3.1, TASK, TASK-1

Related Genes

#	Gene Symbol	Number of hits
1	ATP1B1	1 hits
2	CACNA1C	1 hits
3	CACNA1G	1 hits
4	CACNA1H	1 hits
5	CACNA2D1	1 hits
6	CACNB1	1 hits
7	CACNB2	1 hits
8	CAV3	1 hits
9	GJA1	1 hits
10	GJA4	1 hits
11	HCN2	1 hits
12	KCNA2	1 hits
13	KCNA3	1 hits
14	KCNA4	1 hits
15	KCNAB1	1 hits
16	KCNB1	1 hits
17	KCND1	1 hits
18	KCNE1	1 hits
19	KCNG2	1 hits
20	KCNH2	1 hits
21	KCNIP2	1 hits
22	KCNJ2	1 hits
23	KCNJ3	1 hits
24	KCNK2	1 hits
25	KCNK5	1 hits
26	KCNN2	1 hits
27	KCNQ1	1 hits
28	SCN1B	1 hits
29	SCN5A	1 hits
30	TPM2	1 hits

Related Sentences

#	PMID	Sentence
1	18482733	Western blot analyses revealed that expression of the Kv accessory protein, KChIP2, is also reduced in MHC-PPARalpha ventricles in parallel with the decrease in Kv4.2.
2	18482733	Although the properties of the endogenous and the "augmented" I(ss) suggest a role(s) for two pore domain K(+) channel (K2P) pore-forming subunits, the expression levels of KCNK2 (TREK1), KCNK3 (TASK1) and KCNK5 (TASK2) in MHC-PPARalpha and WT ventricles are not significantly different.
3	22581745	Expression of genes encoding cardiac muscle proteins (Myh6/7, Mybpc3, Myl1/3, Actc1, Tnni3, Tnn2, Tpm1/2/4 and Dbi) and intercellular proteins (Gja1/4/5/7, Dsp and Cav1/3) were unaltered in GK ventricle compared with control ventricle.
4	22581745	The expression of genes encoding some membrane pumps and exchange proteins was unaltered (Atp1a1/2, Atp1b1 and Slc8a1), whilst others were either upregulated (Atp1a3, relative expression 2.61 ± 0.69 versus 0.84 ± 0.23) or downregulated (Slc9a1, 0.62 ± 0.07 versus 1.08 ± 0.08) in GK ventricle compared with control ventricle.
5	22581745	The expression of genes encoding some calcium (Cacna1c/1g, Cacna2d1/2d2 and Cacnb1/b2), sodium (Scn5a) and potassium channels (Kcna3/5, Kcnj3/5/8/11/12, Kchip2, Kcnab1, Kcnb1, Kcnd1/2/3, Kcne1/4, Kcnq1, Kcng2, Kcnh2, Kcnk3 and Kcnn2) were unaltered, whilst others were either upregulated (Cacna1h, 0.95 ± 0.16 versus 0.47 ± 0.09; Scn1b, 1.84 ± 0.16 versus 1.11 ± 0.11; and Hcn2, 1.55 ± 0.15 versus 1.03 ± 0.08) or downregulated (Hcn4, 0.16 ± 0.03 versus 0.37 ± 0.08; Kcna2, 0.35 ± 0.03 versus 0.80 ± 0.11; Kcna4, 0.79 ± 0.25 versus 1.90 ± 0.26; and Kcnj2, 0.52 ± 0.07 versus 0.78 ± 0.08) in GK ventricle compared with control ventricle.
6	23620341	Expression of mRNA encoding Tpm2, Gja4, Atp1b1, Cacna1g, Cacnb2, Hcn2, Kcna3 and Kcne1 were up-regulated and Gja1, Kcnj2 and Kcnk3 were down-regulated in hearts of sedentary GK rats compared to sedentary controls.
7	23620341	Gja1, Cav3 and Kcnk3 were up-regulated and Hcn2 was down-regulated in hearts of exercise trained GK compared to sedentary GK controls.
8	23620341	Expression of mRNA encoding Tpm2, Gja4, Atp1b1, Cacna1g, Cacnb2, Hcn2, Kcna3 and Kcne1 were up-regulated and Gja1, Kcnj2 and Kcnk3 were down-regulated in hearts of sedentary GK rats compared to sedentary controls.
9	23620341	Gja1, Cav3 and Kcnk3 were up-regulated and Hcn2 was down-regulated in hearts of exercise trained GK compared to sedentary GK controls.