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Gene Information
Gene symbol: KIR2DL5B
Gene name:
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | KIR2DL5A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17215859 | Killer immunoglobulin-like receptor (KIR) genes map to the region and encode receptors of natural killer (NK) cells and certain T cells that modulate cytolitic activity through interactions with HLA class I ligands, participating in the innate immune response. |
| 2 | 17215859 | The frequency of gene combination KIR2DL5B(+)/KIR2DL5A(-) was significantly higher in the disease group, and this result was confirmed in a second group of 343 CD patients and 160 controls of Spanish origin, suggesting an implication of this 'unexpressed' gene with increased susceptibility to CD (combined OR of 3.63 (95% CI: 1.76-7.51; P=0.0004)), possibly due to the lack of an efficient inhibitory signal. |