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Gene Information
Gene symbol: KLF14
Gene name:
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDKAL1 | 1 hits |
| 2 | FTO | 1 hits |
| 3 | GCKR | 1 hits |
| 4 | HMGA2 | 1 hits |
| 5 | IRS1 | 1 hits |
| 6 | JAZF1 | 1 hits |
| 7 | KCNQ1 | 1 hits |
| 8 | PPARG | 1 hits |
| 9 | TCF7L2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22791750 | We replicated SNPs in or near SC4MOL and TCERG1L in West Africans. |
| 2 | 22791750 | The meta-analysis of 1497 African Americans and West Africans yielded genome-wide significant associations for SNPs in the SC4MOL gene: rs17046216 (P = 1.7 × 10(-8) and 2.9 × 10(-8) for FI and IR, respectively); and near the TCERG1L gene with rs7077836 as the top scoring (P = 7.5 × 10(-9) and 4.9 × 10(-10) for FI and IR, respectively). |
| 3 | 22791750 | In addition, we replicated previous GWAS findings for IR and FI in Europeans for GCKR, and for variants in four T2D loci (FTO, IRS1, KLF14 and PPARG) which exert their action via IR. |
| 4 | 22791750 | In summary, variants in/near SC4MOL, and TCERG1L were associated with FI and IR in this cohort of African Americans and were replicated in West Africans. |
| 5 | 22791750 | TCERG1L is associated with plasma adiponectin, a key modulator of obesity, inflammation, IR and diabetes. |
| 6 | 23193183 | Our results revealed that seven index SNPs at the TCF7L2, KLF14, KCNQ1, ADCY5, CDKAL1, JAZF1, and GCKR loci were significantly associated with T2D (P < 0.05). |
| 7 | 23193183 | Locus-wide analysis demonstrated significant associations (P(emp) < 0.05) at regional best SNPs in the TCF7L2, KLF14, and HMGA2 loci as well as suggestive signals in KCNQ1 after correction for the effective number of SNPs at each locus. |
| 8 | 23193183 | Our results revealed that seven index SNPs at the TCF7L2, KLF14, KCNQ1, ADCY5, CDKAL1, JAZF1, and GCKR loci were significantly associated with T2D (P < 0.05). |
| 9 | 23193183 | Locus-wide analysis demonstrated significant associations (P(emp) < 0.05) at regional best SNPs in the TCF7L2, KLF14, and HMGA2 loci as well as suggestive signals in KCNQ1 after correction for the effective number of SNPs at each locus. |