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Gene Information
Gene symbol: KRT8
Gene name: keratin 8
HGNC ID: 6446
Synonyms: CARD2, K8, CK8, CYK8, K2C8, KO
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | B3GAT1 | 1 hits |
| 2 | CCND1 | 1 hits |
| 3 | CEACAM5 | 1 hits |
| 4 | EGF | 1 hits |
| 5 | EGFR | 1 hits |
| 6 | ETFA | 1 hits |
| 7 | FGF7 | 1 hits |
| 8 | IGF1R | 1 hits |
| 9 | IL1B | 1 hits |
| 10 | ISL1 | 1 hits |
| 11 | JUN | 1 hits |
| 12 | KIT | 1 hits |
| 13 | KRT16 | 1 hits |
| 14 | KRT19 | 1 hits |
| 15 | KRT20 | 1 hits |
| 16 | KRT5 | 1 hits |
| 17 | KRT7 | 1 hits |
| 18 | NCAM1 | 1 hits |
| 19 | NES | 1 hits |
| 20 | PAX4 | 1 hits |
| 21 | PDGFRA | 1 hits |
| 22 | PDX1 | 1 hits |
| 23 | RPS27A | 1 hits |
| 24 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16182777 | Cells characterized by a group of markers (Nestin, CK-8, CK-18) and transcription factors (Isl-1, Pdx-1, Pax-4, Ngn-3) important for beta-cell differentiation have been detected in umbilical cord blood. |
| 2 | 19171978 | Arsenic causes apoptosis via free radical generation, and the cutaneous toxicity is linked to its effect on various cytokines (e.g., IL-8, TGF-beta, TNF-alpha, GM-CSF), growth factors, and transcription factors. |
| 3 | 19171978 | Increased expression of cytokeratins, keratin-16 (marker for hyperproliferation) and keratin-8 and -18 (marker for less differentiated epithelial cells), can be related to the histopathological findings of hyperkeratosis and dysplastic cells in the arsenicosis skin lesion. |
| 4 | 21031338 | It could be shown that the applied anabolic combination significantly influenced the expression of the steroid receptor ERα, the keratinization factor CK8, the proinflammatory interleukins IL-1α and IL-1β, the growth factors FGF7, EGF, EGFR, IGF-1R, TGFα and LTF, the oncogen c-jun and other factors like actinβ and ubiquitin 3. |
| 5 | 23638232 | Immunohistochemically, the lymphoid cells were positive for vimentin, CD3, CD4, CD5, CD8, CD10, CD15, CD20, CD23, CD30, CD43, CD38, CD138, CD45RO, CD79α, bcl-2, bcl-6, κ-chain, λ-chain, and Ki-67 (labeling index=7%). |
| 6 | 23638232 | The lymphoblastic cells were positively labeled for CD15 and CD30. |
| 7 | 23638232 | They were negative for cytokeratin (CK) CAM5.2, CKAE1/3, CK34BE12, CK5/6, CK7, CK8, CK18, CK19, CK20, EMA, CEA, CD56, CD57, p53, KIT, PDGFRA, and cyclin D1. |
| 8 | 23638232 | The low Ki-67 labeling and negative p53 also suggested the diagnosis. |